Description

• General description: We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is a biorenewable and thus aligns with "Safer Solvents and Auxiliaries" and "Use of Renewable Feedstocks". Click here for more information.2-Methyltetrahydrofuran (2-MTHF), a 2-methyl substituted tetrahydrofuran, is a biomass derived solvent. It is a potential greener solvent alternative for organic synthesis.[1] It shows resistance to reduction by lithium making it a promising candidate as electrolytes in lithium batteries.[2] Its polarity and Lewis base strength is intermediate between tetrahydrofuran (THF) and diethyl ether.[3] The ring opening reaction of 2-MTHF has been studied using acid chloride and iodide.[4]
• Application: 2-Methyltetrahydrofuran may be used as a solvent for phosphatidylserine synthesis.[5]It may be used as an alternative solvent to:Dimethyl sulfoxide (DMSO) or methyl tert-butyl ether (MTBE) in the C-C bond forming reactions catalyzed by lyase enzyme.[6]Tetrahydrofuran (THF) in the reaction between Grignard reagents and carbonyl compounds.[7]Methylene chloride in some biphasic reactions.[8]Green Alternatives to DCM and THF from Renewable ResourcesOrganic Solar Cells2-Methyltetrahydrofuran (2-MeTHF): A Biomass-Derived Solvent with Broad Application in Organic Chemistry
• Features and Benefits: Greener alternative for THF, DCM, DMSO, and MTBE