Polymyxin B solution
1 mg/mL in H2O, analytical standard
Manufacturer: Supelco
CAS Number: 1405-20-5
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 ML | 81271-10-ML | In Stock | ₹ 8,086.28 |
81271 - 10 ML
In Stock
Quantity
1
Base Price: ₹ 8,086.28
GST (18%): ₹ 1,455.53
Total Price: ₹ 9,541.81
grade
analytical standard
Quality Level
100
concentration
1 mg/mL in H2O
technique(s)
HPLC: suitablegas chromatography (GC): suitable
antibiotic activity spectrum
Gram-negative bacteriaGram-positive bacteriafungi
application(s)
pharmaceutical (small molecule)
format
single component solution
Mode of action
cell membrane | interferes
storage temp.
2-8°C
InChI
1S/C48H82N16O13.H2O4S/c1-27(2)24-37-47(76)59-32(11-19-52)41(70)56-31(10-18-51)43(72)61-35(14-22-65)39(68)54-21-13-34(45(74)57-33(12-20-53)44(73)64-38(48(77)63-37)25-28-6-4-3-5-7-28)60-42(71)30(9-17-50)58-46(75)36(15-23-66)62-40(69)29(8-16-49)55-26-67;1-5(2,3)4/h3-7,26-27,29-38,65-66H,8-25,49-53H2,1-2H3,(H,54,68)(H,55,67)(H,56,70)(H,57,74)(H,58,75)(H,59,76)(H,60,71)(H,61,72)(H,62,69)(H,63,77)(H,64,73);(H2,1,2,3,4)
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | TOKU-E Polymyxin B ReadyMade™ Solution, 1405-20-5, 10 ML | -- | ₹ 13,261.80 | |
| | Polymyxin B Solution, 1 mg/mL in Water, MilliporeSigma™ Supelco™ | -- | ₹ 10,831.90 | |
| | U.S. Pharmacopeia Polymyxin B sulphate | 1405-20-5 | 1301.6 g/mol | 200MG | -- | ₹ 28,613.83 | |
| | Polymyxin B Sulfate Pharmaceutical Secondary Standard, MilliporeSigma™ Supelco™ | -- | ₹ 12,200.86 | |
| | Polymyxin B Sulfate, TCI America™ | -- | ₹ 13,321.69 | |
| | Sigma Aldrich Fine Chemicals Biosciences Polymyxin B sulfate United States Pharmacopeia (USP) Reference Standard | 1405-20-5 | 200MG | -- | ₹ 45,791.71 | |
| | TOKU-E Polymyxin B Sulfate, USP, 1405-20-5, 100 MU | -- | ₹ 41,496.60 | |
| | TOKU-E Polymyxin B Sulfate, USP, 1405-20-5, 10 MU | -- | ₹ 10,780.56 | |
| | Enzo Life Sciences Polymyxin B . sulfate (1g). CAS: 1405-20-5 | -- | ₹ 8,953.85 | |
| | Polymyxin B Sulfate | -- | ₹ 10,435.30 |
Related Products
Description
- General description: Chemical structure: peptide
- Application: Polymyxin B sulfate is a strongly cationic cyclic polypeptide antibiotic that is derived from fermentation of Bacilus polymyxa. It is a mixture of B1 and B2 sulfate. The product has been used clinically to treat infections of the urinary tract, meninges and blood stream caused by susceptible strains of Pseudomonas aeruginosa. It also has uses studying multidrug-resistant pathogens, as an immobilized agent for removal of endotoxins, and to induce pore formation in the membranes of cortex cells from excised sorghum roots.
- Biochem/physiol Actions: Mode of Action: Polymyxin B Sulfate binds to the lipid A portion of bacterial lipopolysaccharides, disrupting the cytoplasmic membrane by inducing pores large enough to permit nucleotide leakage in bacterial walls. This disrupts the permeability of the cytoplasmic membrane. Mode of Resistance: The activity of Polymyxin B sulfate is inhibited by iron(II), Co(II), Mn(II) and Magnesium ions. Polymyxin B may also be incompaitible with other microbial agents, including amphoterecin, cephalothin sodium, cephasolin sodium and heparin sodium. Antimicrobial Spectrum: Has bactericidal action on most gram-negative bacilli, including E. Coli and on most fungi and gram-positive bacteria.
- Preparation Note: This product is concentrated at 1 mg/mL in water, and should be stored at 2-8°C.
SAFETY INFORMATION
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves