Description

• Application: Optimizing high-throughput viral vector characterization with density gradient equilibrium analytical ultracentrifugation.: This study utilizes cesium chloride for optimizing high-throughput characterization of viral vectors using density gradient equilibrium analytical ultracentrifugation, enhancing the efficiency and accuracy of viral vector analysis. (Sternisha et al., 2023). Mammalian Reoviruses: Propagation, Quantification, and Storage.: Cesium chloride is used in this study to facilitate the propagation, quantification, and storage of mammalian reoviruses, contributing to better handling and study of these viruses in research settings. (Coombs, 2023). Large-scale purification of functional AAV particles packaging the full genome using short-term ultracentrifugation with a zonal rotor.: This paper discusses the large-scale purification of adeno-associated virus particles using cesium chloride in ultracentrifugation, which is crucial for gene therapy applications. (Wada et al., 2023).
• Analysis Note: Purity (metallic): ≥ 99.995 %Assay (argentometric): ≥ 99.5 %Specific absorbance (260 nm; 50 %; 1 cm; water): ≤ 0.020Specific absorbance (280 nm; 50 %; 1 cm; water): ≤ 0.020Phosphate (PO₄): ≤ 10 ppmSulfate (SO₄): ≤ 20 ppmTotal nitrogen (N): ≤ 10 ppmAl (Aluminium): ≤ 0.05 ppmB (Boron): ≤ 0.05 ppmBa (Barium): ≤ 2.0 ppmCa (Calcium): ≤ 0.50 ppmCd (Cadmium): ≤ 0.005 ppmCe (Cerium): ≤ 0.005 ppmCo (Cobalt): ≤ 0.005 ppmCr (Chromium): ≤ 0.005 ppmCu (Copper): ≤ 0.005 ppmEu (Europium): ≤ 0.005 ppmFe (Iron): ≤ 0.020 ppmK (Potassium): ≤ 2 ppmLa (Lanthanum): ≤ 0.005 ppmLi (Lithium): ≤ 0.2 ppmMg (Magnesium): ≤ 0.10 ppmMn (Manganese): ≤ 0.010 ppmNa (Sodium): ≤ 4.0 ppmNi (Nickel): ≤ 0.020 ppmPb (Lead): ≤ 0.030 ppmRb (Rubidium): ≤ 5 ppmSc (Scandium): ≤ 0.005 ppmSm (Samarium): ≤ 0.005 ppmSr (Strontium): ≤ 0.20 ppmTl (Thallium): ≤ 0.20 ppmY (Yttrium): ≤ 0.005 ppmYb (Ytterbium): ≤ 0.005 ppmZn (Zinc): ≤ 0.020 ppm
• Legal Information: SUPRAPUR is a registered trademark of Merck KGaA, Darmstadt, Germany