Description

• Application: Validation of a simple liquid chromatography coupled to tandem mass spectrometry method for the simultaneous determination of tacrolimus, sirolimus, everolimus and cyclosporin A in dried matrix on paper discs.: This study validates a liquid chromatography-mass spectrometry method enhanced by zinc sulfate heptahydrate for analyzing immunosuppressant drugs. This development represents a significant advance in clinical diagnostics, providing faster and more reliable drug monitoring (Bressán et al., 2021). Adduct simplification in the analysis of cyanobacterial toxins by matrix-assisted laser desorption/ionization mass spectrometry.: Research utilizing zinc sulfate heptahydrate in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry to simplify the analysis of cyanobacterial toxins. This study enhances the understanding of environmental toxins, showcasing the role of zinc sulfate heptahydrate in improving analytical accuracy and efficiency (Howard et al., 2007).
• Linkage: Replaces: ZX0105; ZX0105-1; ZX0105-20
• Analysis Note: Assay (complexometric): 99.5 - 103.0 %Identity: passes testAppearance of solution: passes testInsoluble matter: ≤ 0.01 %pH-value (5 %; water, 25 °C): 4.4 - 5.6Chloride (Cl): ≤ 0.0005 %Total nitrogen (N): ≤ 0.0005 %Nitrate (NO₃): ≤ 0.002 %As (Arsenic): ≤ 0.00005 %Ca (Calcium): ≤ 0.001 %Cd (Cadmium): ≤ 0.0005 %Cu (Copper): ≤ 0.0005 %Fe (Iron): ≤ 0.0005 %K (Potassium): ≤ 0.001 %Mg (Magnesium): ≤ 0.001 %Mn (Manganese): ≤ 0.0003 %Na (Sodium): ≤ 0.001 %NH₄ (Ammonium): ≤ 0.001 %Pb (Lead): ≤ 0.001 %Corresponds to ACS, ISO, Reag. Ph Eur
• Legal Information: EMSURE is a registered trademark of Merck KGaA, Darmstadt, Germany