(N-Succinimidyloxycarbonylmethyl)tris(2,4,6-trimethoxyphenyl)phosphonium bromide
for protein sequence analysis (by MALDI-MS), ≥98.5%
Manufacturer: Supelco
CAS Number: 226409-58-1
Synonym(S): N-Succinimidyl [tris(2,4,6-trimethoxyphenyl)phosphonio]acetate bromide, TMPP-Ac-OSu
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 50 MG | 29208-50-MG | In Stock | ₹ 18,456.63 |
29208 - 50 MG
In Stock
Quantity
1
Base Price: ₹ 18,456.63
GST (18%): ₹ 3,322.193
Total Price: ₹ 21,778.823
grade
for protein sequence analysis (by MALDI-MS)
Quality Level
100
Assay
≥98.5% (HPLC)≥98.5%
technique(s)
MALDI-MS: suitable
mp
199-205 °C (dec.)
storage temp.
−20°C
SMILES string
[Br-].COc1cc(OC)c(c(OC)c1)[P+](CC(=O)ON2C(=O)CCC2=O)(c3c(OC)cc(OC)cc3OC)c4c(OC)cc(OC)cc4OC
InChI
1S/C33H39NO13P.BrH/c1-38-19-12-22(41-4)31(23(13-19)42-5)48(18-30(37)47-34-28(35)10-11-29(34)36,32-24(43-6)14-20(39-2)15-25(32)44-7)33-26(45-8)16-21(40-3)17-27(33)46-9;/h12-17H,10-11,18H2,1-9H3;1H/q+1;/p-1
InChI key
YKMSQZIYVKTUHI-UHFFFAOYSA-M
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | 226409-58-1 | (N-Succinimidyloxycarbonyl-methyl)tris(2,4,6-trimethoxyphenyl)phosphonium Bromide | -- | ₹ 37,047.48 |
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Description
- General description: N-Succinimidyloxycarbonylmethyl tris(2,4,6-trimethoxyphenyl)phosphonium bromide (TMPP-Ac-OSu) is an acylating reagent, and is generally used for the selective derivatization of N-terminal a-amino group of peptide. The TMPP-acetylated peptides undergo fragmentation thereby creating a-type ions, thus obtaining sequence information becomes easier, even without the usage of automated computational approach.[1] It can be used as a labelling reagent in liquid chromatography-coupled mass spectrometry (LC-MS/MS) of N-terminal peptides, so as to improve ionization efficiency, simplify fragmentation, and retention times, thereby leading to better separation of peptides.[2]
- Application: TMPP-Ac-OSu was used for labelling peptides, in tandem mass spectrometry, done for converting arginine to ornithine, in order to improve the fragmentation pattern of peptides.[1]
- Packaging: Bottomless glass bottle. Contents are inside inserted fused cone.
- Other Notes: Reagent for modifying N-termial of peptides for fast atom bombardment, FAB or matrix assisted laser desorption/ionization MS, MALDI MS[3][4]
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves