04725

3-Hydroxyglutaric acid

analytical standard

Manufacturer: Supelco

CAS Number: 638-18-6

Synonym(S): β-Hydroxyglutaric acid, 3-Hydroxypentanedioic acid

Select a Size

Pack Size SKU Availability Price
10 MG 04725-10-MG In Stock ₹ 22,949.00
50 MG 04725-50-MG In Stock ₹ 1,06,366.45

04725 - 10 MG

₹ 22,949.00

In Stock

Quantity

1

Base Price: ₹ 22,949.00

GST (18%): ₹ 4,130.82

Total Price: ₹ 27,079.82

grade

analytical standard

Quality Level

100

Assay

≥95.0% (GC)

shelf life

limited shelf life, expiry date on the label

application(s)

clinical testing

format

neat

storage temp.

2-8°C

InChI

1S/C5H8O5/c6-3(1-4(7)8)2-5(9)10/h3,6H,1-2H2,(H,7,8)(H,9,10)

InChI key

ZQHYXNSQOIDNTL-UHFFFAOYSA-N

Other Options

Image Product Name Manufacturer Price Range
3-Hydroxyglutaric acid, ≥95% (GC), MilliporeSigma™ Supelco™
-- ₹ 1,00,019.64
638-18-6 | 3-Hydroxypentanedioic acid
-- ₹ 2,823.48 - ₹ 1,21,837.44

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Description

  • Biochem/physiol Actions: 3-Hydroxyglutaric acid is a glutaric acid derivative which is the byproduct of glutaric acidemia type I. Glutaric aciduria type I (glutaryl-CoA dehydrogenase deficiency) is an inborn error of metabolism that usually manifests in infancy by an acute encephalopathic crisis and often results in permanent motor handicap. Studies indicate that 3-hydroxyglutaric acid can be used as biomarker for GCDH (glutaryl-CoA dehydrogenase) deficiency. It is believed that the excretion of 3-hydroxyglutaric acid is increased during ketosis, which occurs during glutaryl-CoA dehydrogenase deficiency. Studies on striatal cultures show that IGF-1 and FGF-2 (bFGF) reduces 3-hydroxyglutaric acid toxicity in striatal neurons.
  • Recommended products: Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

SAFETY INFORMATION

WGK

WGK 3