32417

Natamycin

VETRANAL®, analytical standard

Manufacturer: Supelco

CAS Number: 7681-93-8

Synonym(S): Pimaricin, Natamycin

Select a Size

Pack Size SKU Availability Price
50 MG 32417-50-MG In Stock ₹ 14,429.73

32417 - 50 MG

₹ 14,429.73

In Stock

Quantity

1

Base Price: ₹ 14,429.73

GST (18%): ₹ 2,597.351

Total Price: ₹ 17,027.081

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitablegas chromatography (GC): suitable

application(s)

cleaning productscosmeticsfood and beveragespersonal care

format

neat

storage temp.

2-8°C

SMILES string

C[C@@H]1C\C=C\C=C\C=C\C=C\[C@@H](C[C@@H]2O[C@](O)(C[C@@H](O)C[C@H]3O[C@@H]3\C=C\C(=O)O1)C[C@H](O)[C@H]2C(O)=O)O[C@@H]4O[C@H](C)[C@@H](O)[C@H](N)[C@@H]4O

InChI

1S/C33H47NO13/c1-18-10-8-6-4-3-5-7-9-11-21(45-32-30(39)28(34)29(38)19(2)44-32)15-25-27(31(40)41)22(36)17-33(42,47-25)16-20(35)14-24-23(46-24)12-13-26(37)43-18/h3-9,11-13,18-25,27-30,32,35-36,38-39,42H,10,14-17,34H2,1-2H3,(H,40,41)/b4-3+,7-5+,8-6+,11-9+,13-12+/t18-,19-,20+,21+,22+,23-,24-,25+,27-,28+,29-,30+,32+,33-/m1/s1

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Description

  • General description: Natamycin is a polyene antibiotic that generally finds application as an antifungal agent as it lacks development of resistance and has a broad spectrum of activity. However, its mode of action is yet unclear, direct binding and isothermal titration calorimetry studies has revealed that natamycin binds specifically to ergosterol present in model membranes.[1][2]
  • Application: Natamycin may be used as an analytical reference standard for the quantification of the analyte in wine samples using high-performance liquid chromatography coupled to electrospray ionization in positive mode high resolution mass spectrometry (HPLC-ESI-HR-MS)[3] and reversed-phase high-performance liquid chromatography-tandem mass spectrometry technique (UHPLC-MS/MS).[4]
  • Biochem/physiol Actions: An antifungal polyene macrolide that binds specifically to ergosterol and blocks fungal growth. However, unlike nysatin and filipin, pimaricin does not change the permeability of the plasma membrane
  • Legal Information: VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFETY INFORMATION

WGK

WGK 3