Cyclosporin A
VETRANAL®, analytical standard
Manufacturer: Supelco
CAS Number: 59865-13-3
Synonym(S): Antibiotic S 7481F1, Cyclosporine
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 100 MG | 32425-100-MG | In Stock | ₹ 36,385.80 |
32425 - 100 MG
In Stock
Quantity
1
Base Price: ₹ 36,385.80
GST (18%): ₹ 6,549.444
Total Price: ₹ 42,935.244
grade
analytical standard
Quality Level
100
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitablegas chromatography (GC): suitable
application(s)
forensics and toxicologypharmaceutical (small molecule)
format
neat
SMILES string
CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O)C(C)C
InChI
1S/C62H111N11O12/c1-25-27-28-40(15)52(75)51-56(79)65-43(26-2)58(81)67(18)33-48(74)68(19)44(29-34(3)4)55(78)66-49(38(11)12)61(84)69(20)45(30-35(5)6)54(77)63-41(16)53(76)64-42(17)57(80)70(21)46(31-36(7)8)59(82)71(22)47(32-37(9)10)60(83)72(23)50(39(13)14)62(85)73(51)24/h25,27,34-47,49-52,75H,26,28-33H2,1-24H3,(H,63,77)(H,64,76)(H,65,79)(H,66,78)/b27-25+/t40-,41+,42-,43+,44+,45+,46+,47+,49+,50+,51+,52-/m1/s1
InChI key
PMATZTZNYRCHOR-CGLBZJNRSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Sigma Aldrich Fine Chemicals Biosciences Ciclosporin European Pharmacopoeia (EP) Reference Standard | 59865-13-3 | MFCD00274558 | | -- | ₹ 23,582.90 | |
| | Cyclosporine Pharmaceutical Secondary Standard, MilliporeSigma™ Supelco™ | -- | ₹ 23,143.98 | |
| | Sigma Aldrich Fine Chemicals Biosciences Cyclosporin A | 59865-13-3 | MFCD00274558 | 5mg | -- | ₹ 31,652.92 | |
| | Sigma Aldrich Fine Chemicals Biosciences Cyclosporin A, Ready Made Solution 1 mg/mL in DMSO (0.2 μm-filtered) | 59865-13-3 | 1ml | -- | ₹ 17,189.00 | |
| | eMolecules Medchem Express / Cyclosporin A / 100mg / 446273016 / HY-B0579 / / 59865-13-3 / MFCD00274558 / 1202.635 / C62H111N11O12 | -- | ₹ 7,556.66 | |
| | Enzo Life Sciences Cyclosporin A (500mg). CAS: 59865-13-3 | -- | ₹ 30,403.75 | |
| | Cyclosporine | -- | ₹ 18,175.18 | |
| | Cyclosporin A solution | -- | ₹ 27,038.90 | |
| | Cyclosporine | -- | ₹ 1,51,182.00 | |
| | Ciclosporin for system suitability A | -- | ₹ 14,970.98 |
Related Products
Description
- General description: Cyclosporin A (CsA) is a fungal metabolite, a cyclic undecapeptide. It has highly specific immunosuppressive effects with low myelotoxicity, thereby making it a valuable drug in human organ transplantation. Its immunosuppressive activity is based upon its ability to inhibit early steps of T-lymphocyte activation such as lymphokine gene transcription.[1][2][3]
- Application: Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
- Biochem/physiol Actions: A fungal metabolite possessing potent immunosuppressive properties. It inhibits the T-cell receptor signal transduction pathway via the formation of cyclosporin A−cyclophilin complex that inhibits calcineurin (protein phosphatase 2B). Inhibits nitric oxide synthesis induced by interleukin 1α, lipopolysaccharides and TNFα. Can block cytochrome c release from mitochondria.
- Legal Information: VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Carc. 1B - Repr. 1B
WGK
WGK 3