PHL80506

Nitidine chloride

phyproof® Reference Substance

Manufacturer: Sigma Aldrich

CAS Number: 13063-04-2

Synonym(S): 2,3-Dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridinium chloride, NSC 146397

Select a Size

Pack Size SKU Availability Price
10 MG PHL80506-10-MG In Stock ₹ 48,788.28

PHL80506 - 10 MG

₹ 48,788.28

In Stock

Quantity

1

Base Price: ₹ 48,788.28

GST (18%): ₹ 8,781.89

Total Price: ₹ 57,570.17

grade

primary reference standard

product line

phyproof® Reference Substance

Assay

≥98.0% (HPLC)

manufacturer/tradename

PhytoLab

format

neat

SMILES string

C[N+]1=CC2=CC(OC)=C(OC)C=C2C3=CC=C4C=C5C(OCO5)=CC4=C31.[Cl-]

InChI

1S/C21H18NO4.ClH/c1-22-10-13-7-17(23-2)18(24-3)8-15(13)14-5-4-12-6-19-20(26-11-25-19)9-16(12)21(14)22;/h4-10H,11H2,1-3H3;1H/q+1;/p-1

InChI key

QLDAACVSUMUMOR-UHFFFAOYSA-M

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Description

  • General description: This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
  • Biochem/physiol Actions: Nitidine chloride is a natural product with anti-cancer activity. Its mechanism of action likely involves several pathways. Nitidine chloride has been found to inhibit topoisomerase I and topoisomerase II, induce cell apoptosis by activation of the caspase-dependent pathway, suppress c-Src/FAK associated signaling pathways and suppress Janus kinase 2/STAT3 signaling and the expression of STAT3-dependent target genes, including cyclin D1, Bcl-xL, and VEGF. Nitidine chloride has also been found to have anti-malaria activity.
  • Legal Information: phyproof is a registered trademark of PhytoLab GmbH & Co. KG

SAFETY INFORMATION

Pictograms

GHS06

Signal Word

Danger

Hazard Statements

H300

Precautionary Statements

P301 + P310 + P330

Hazard Classifications

Acute Tox. 2 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable