7069429
Mouse IgM Isotype Control (11E10), eBioscience™, Invitrogen™
Mouse Isotype Control
Manufacturer: Fischer Scientific
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Antigen
Mouse IgM
Concentration
0.5 mg/mL
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Not Applicable
Gene Alias
AGM1; AI326478; Igh6; Igh-6; Ighm; Igh-M; Igm; immunoglobulin heavy constant mu; MU; muH; VH
Primary or Secondary
Isotype Control (Primary)
Content And Storage
4° C
Clone
11E10
Applications
Control, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 0.09% sodium azide; pH 7.2
Isotype
IgM
Purification Method
Affinity chromatography
Related Products
Description
- Description: The mouse IgM is useful as an isotype control immunoglobulin
- The immunoglobulin was generated by immunization with lipopolysaccharide (LPS)
- The immunoglobulin is reactive with LPS
- Applications Reported: This mouse IgM isotype control has been reported for use in immunocytochemistry, immunohistochemistry, and flow cytometric analysis
- Applications Tested: Mouse IgM Isotype Control Purified has been tested by flow cytometric analysis
- Use at the same concentration as the experimental antibody
- Purity: Greater than 90%, as determined by SDS-PAGE
- Aggregation: Less than 10%, as determined by HPLC
- Filtration: 0.2 μm post-manufacturing filtered
- Mouse IgM is an immunoglobulin M antibody that is produced by B cells in response to an antigen
- It is the first antibody produced during an immune response and is the largest immunoglobulin in the serum
- Mouse IgM is composed of five heavy chains and five light chains, and it is involved in complement activation and agglutination of antigens
- It plays a crucial role in the innate immune response and is important for neutralizing pathogens before the adaptive immune response is fully activated
- Mouse IgM is widely used in research and diagnostic applications, including ELISA, Western blotting, and immunohistochemistry.