Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), APC, eBioscience™, Invitrogen™

Description

• Description: The monoclonal mouse IgG1 K immunoglobulin is useful as an isotype control
• Applications Reported: APC Mouse IgG1 K Isotype Control has been reported for use in flow cytometric analysis
• Applications Tested: The Mouse IgG1 K Isotype Control is offered in 2 formats:- μg size: This can be used at the same concentration as the experimental antibody
• - test size: has been pre-titrated and tested by intracellular staining for flow cytometric analysis
• This can be used at test size: 5 μL (0.5 μg) per test
• A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
• Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
• Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser
• Filtration: 0.2 μm post-manufacturing filtered
• Mouse IgG1 is a subtype of immunoglobulin G antibody that is produced by B cells in response to an antigen
• It is the most abundant IgG subtype in the serum and plays a crucial role in the adaptive immune response
• Mouse IgG1 is composed of two heavy chains and two light chains, and it is involved in opsonization, complement activation, and antibody-dependent cell-mediated cytotoxicity
• It is also involved in the regulation of immune responses, including the activation of T cells and the inhibition of B cell activation
• Mouse IgG1 is widely used in research and diagnostic applications, including ELISA, Western blotting, and immunohistochemistry
• It is also used in therapeutic applications, such as immunotherapy and vaccine development.