7092304

Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), eFluor™ 660, eBioscience™, Invitrogen™

Mouse Isotype Control

Manufacturer: Fischer Scientific

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Antigen

Mouse IgG1 kappa

Concentration

0.2 mg/mL

Conjugate

eFluor 660

Host Species

Mouse

Target Species

Not Applicable

Gene Alias

IgG1; Igh-4; Ighg1; Immunoglobulin G; Immunoglobulin G1; immunoglobulin heavy constant gamma 1 (G1m marker); ImmunoglobulinG; ImmunoglobulinG1; VH7183

Primary or Secondary

Isotype Control (Primary)

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Clone

P3.6.2.8.1

Applications

Control, Flow Cytometry, Immunohistochemistry

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.09% sodium azide; pH 7.2

Isotype

IgG1 κ

Purification Method

Affinity chromatography

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Description

  • Description: The monoclonal mouse IgG1 K immunoglobulin is useful as an isotype control
  • Applications Reported: The Mouse IgG1 K Isotype Control has been reported for use in flow cytometric analysis and immunohistochemical staining
  • Applications Tested: The Mouse IgG1 K Isotype Control has been tested by flow cytometric analysis of normal human peripheral blood cells
  • This can be used at the same concentration as the experimental antibody
  • eFluor® 660 is a replacement for Alexa Fluor® 647
  • eFluor® 660 emits at 659 nm and is excited with the red laser (633 nm)
  • Please make sure that your instrument is capable of detecting this fluorochome
  • Excitation: 633-647 nm; Emission: 668 nm; Laser: Red Laser
  • Filtration: 0.2 μm post-manufacturing filtered
  • Mouse IgG1 is a subtype of immunoglobulin G antibody that is produced by B cells in response to an antigen
  • It is the most abundant IgG subtype in the serum and plays a crucial role in the adaptive immune response
  • Mouse IgG1 is composed of two heavy chains and two light chains, and it is involved in opsonization, complement activation, and antibody-dependent cell-mediated cytotoxicity
  • It is also involved in the regulation of immune responses, including the activation of T cells and the inhibition of B cell activation
  • Mouse IgG1 is widely used in research and diagnostic applications, including ELISA, Western blotting, and immunohistochemistry
  • It is also used in therapeutic applications, such as immunotherapy and vaccine development.