DTX3L Polyclonal Antibody, Invitrogen™
Manufacturer: Invitrogen
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 72-039-4-Each-of-1 | In Stock | ₹ 42,780.00 |
72-039-4 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,780.00
GST (18%): ₹ 7,700.40
Total Price: ₹ 50,480.40
Antigen
DTX3L
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DTX3L
Gene Alias
AU042200; Bbap; BC023741; B-lymphoma- and BAL-associated protein; deltex 3 like, E3 ubiquitin ligase; deltex 3-like; deltex 3-like (Drosophila); deltex E3 ubiquitin ligase 3L; DTX3L; E3 ubiquitin-protein ligase DTX3L; Protein deltex-3-like; RGD1565144; rhysin 2; Rhysin2; rhysin-2; RING-type E3 ubiquitin transferase DTX3L
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
151636
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.4
Gene Accession No.
Q8TDB6
Gene Symbols
DTX3L
Immunogen
Peptide corresponding to human DTX3L [1) aa709-aa728 2) aa194-aa213]
Quantity
100μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody is predicted to react with Monkey, Bovine, Pig, Cat
- Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection
- Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends
- Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways
- Promotes binding of POT1 to single-stranded telomeric DNA
- Modulates the inhibitory effects of POT1 on telomere elongation
- The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity
- May play a role in organogenesis.