FANCD2 Monoclonal Antibody (FI-17), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | AMPA6570-Each-of-1 | In Stock | ₹ 45,817.38 |
AMPA6570 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,817.38
GST (18%): ₹ 8,247.128
Total Price: ₹ 54,064.508
Antigen
FANCD2
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites with 0.1% sodium azide
Gene Accession No.
Q9BXW9
Gene Symbols
FANCD2
Immunogen
FANCD2 fusion protein
Regulatory Status
RUO
Gene ID (Entrez)
2177
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
ChIP Assay, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone
FI-17
Conjugate
Unconjugated
Gene
FANCD2
Gene Alias
2410150O07Rik; AU015151; BB137857; DKFZp762A223; FA4; FACD; FACD2; FAD; FAD2; FA-D2; FANCD; FANCD2; Fanconi anemia complementation group D2; Fanconi anemia D2 protein; Fanconi anemia group D2 protein; Fanconi anemia group D2 protein homolog; Fanconi anemia, complementation group D2; FLJ23826; Protein FACD2
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- By Western blot, this antibody recognizes a band at ∽155 and ∽162 kDa (post-translationally modified form)
- Suggested positive control: Hela whole cell extract
- FANCD2 (Fanconi anemia group D2 protein) is required for maintenance of chromosomal stability
- It promotes accurate and efficient pairing of homologs during meiosis
- FANCD2 is involved in the repair of DNA double-stranded breaks, both by homologous recombination and single-stranded annealing
- It is required for the targeting/stabilization of BLM to non-centromeric abnormal structures induced by replicative stress
- FANCD2 promotes BRCA2/FANCD1 loading onto damaged chromatin
- Defects in the FANCD2 gene result in Fanconi anemia complementation group D2
- This disorder affects all bone marrow elements resulting in anemia, leukopenia, and thrombopenia.