ERK1 Monoclonal Antibody (12D11), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA113041-Each-of-1 | In Stock | ₹ 48,084.72 |
PIMA113041 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,084.72
GST (18%): ₹ 8,655.25
Total Price: ₹ 56,739.97
Antigen
ERK1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.
P27361, Q63844
Gene Symbols
MAPK3
Immunogen
Full-length human recombinant protein expressed in bacteria.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate
Product Type
Antibody
Isotype
IgG
Applications
ChIP Assay, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone
12D11
Conjugate
Unconjugated
Gene
MAPK3
Gene Alias
ERK; Erk1; ERK-1; Ert2; Esrk1; Extracellular signal-regulated kinase 1; extracellular signal-related kinase 1; HS44KDAP; HUMKER1A; Insulin-stimulated MAP2 kinase; MAP kinase 1; MAP kinase 3; MAP kinase isoform p44; MAP kinase2; MAPK 1; MAPK 3; MAPK1; MAPK2; MAPK3; Microtubule-associated protein 2 kinase; mitogen activated protein kinase 3; mitogen-activated 3; mitogen-activated protein kinase 1; mitogen-activated protein kinase 3; MNK1; Mtap2k; p44; p44 MAP kinase; P44ERK1; p44-ERK1; P44MAPK; p44-MAPK; pp42/MAP kinase; PRKM3
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
26417, 5595
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- MA1-13041 detects ERK1 from human, mouse, and monkey samples
- MA1-13041 does not cross react with ERK2
- MA1-13041 has been successfully used in Western blot, ChIP, immunofluoresence, and immunohistochemistry procedures
- By Western blot, this antibody detects a 44 kDa protein corresponding to ERK1
- The MA1-13041 antigen is a recombinant protein corresponding to the full-length sequence of human ERK1
- MAPK3 (ERK1) is a serine/threonine kinase that is an important activator of p90, RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway
- ERK1 is widely expressed and involved in the regulation of meiosis, mitosis, and post-mitotic functions in differentiated cells
- Many different stimuli, including growth factors, cytokines, virus infection, ligands for heterotrimeric guanine nucleotide-binding protein (G protein)-coupled receptors and transforming agents, activate the ERK1 and ERK2 pathways
- Functionally, ERK1 is involved with a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals
- ERK1 is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets
- Alternatively spliced transcript variants encoding different protein isoforms of ERK1 have been described.