4605324

MP Biomedicals™ Bradykinin

Pro-inflammatory peptide acting through G-protein-coupled receptors

Manufacturer: Fischer Scientific

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Purity

>99%

Format

Powder

Product Type

Bradykinin

Content And Storage

-20°C

Molecular Weight (g/mol)

1060.22

Sequence

H2N-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH

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Description

  • Bradykinin activates sphingolipid metabolism
  • Fibroblasts treated with bradykinin produce a rapid and important increase in ceramide which is followed by a transient rise in sphingosine content
  • The peptide also increases ceramide cellular content by rapidly mobilizing neutral glycolipids
  • Bradykinin plays an important role in the regulation of fluid and electrolyte balance, smooth muscle contraction, vasodilation and capillary permeability
  • The bradykinin potentiators, which possess no bradykinin activity themselves, enhance the activity of bradykinin
  • Synonyms: Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg CAS Number: 5979-11-3 EC Number: 227-781-2 Physical Appearance: White powder Format: Supplied as acetate salt Soluble in 0.1M HOAc (25mg/mL)