5545608
Tocris Bioscience™ TAK 960 hydrochloride
Potent and selective PLK1 inhibitor
Manufacturer: Fischer Scientific
CAS Number: 2108449-45-0
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Purity
>98%
Description
TAK 960 hydrochloride
Product Type
TAK 960 hydrochloride
CAS
2108449-45-0
Molecular Weight (g/mol)
598.06
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ TAK 960 hydrochloride | -- | ₹ 1,39,976.16 | |
| | Tocris Bioscience™ TAK 960 hydrochloride | -- | ₹ 33,496.74 |
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Description
- Potent PLK1 inhibitor (IC50 values are 0.8, 16.9 and 50.2 nM for PLK1, PLK2 and PLK3 respectively)
- Exhibits >20-fold selectivity for PLK1 over FAK, MLCK and FES, and has minimal activity against a panel of 282 other kinases
- Inhibits proliferation of a range of cancer cell lines in vitro and inhibits tumor growth of multiple human cancer cell xenografts in vivo
- Orally bioavailable.