PEP0127

Invitrogen™ Human PUMA Synthetic Peptide

Manufacturer: Invitrogen™

Select a Size

Pack Size SKU Availability Price
Each of 1 PEP0127-Each-of-1 In Stock ₹ 16,247.84

PEP0127 - Each of 1

₹ 16,247.84

In Stock

Quantity

1

Base Price: ₹ 16,247.84

GST (18%): ₹ 2,924.611

Total Price: ₹ 19,172.451

Gene ID (Entrez)

27113

Purification Method

purified

Common Name

Human PUMA

Content And Storage

-20°C

Format

Liquid

For Use With (Application)

Blocking Assay, Control

Lyophilized

No

Product Type

Peptide

Regulatory Status

RUO - research use only

Species

Human

Accession Number

Q96PG8

Concentration

200 μg/mL

Description

Synthetic Peptide

Formulation

PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Symbol

BBC3

Preservative

0.02% sodium azide

Quantity

50 μg

Storage Buffer

PBS

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Description

  • PUMA Synthetic Peptide, PEP-0127, from Invitrogen
  • PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53
  • The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b
  • PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53
  • PUMA may be a direct mediator of p53-induced apoptosis
  • Antisense inhibition of PUMA expression reduced the apoptotic response to p53, and PUMA is likely to play a role in mediating p53-induced cell death through the cytochrome c/Apaf-1-dependent pathway
  • This peptide corresponds to 14 amino acids near the carboxy terminus of human PUMA.PEP-0127 can be used as a blocking peptide with polyclonal antibody PA5-20007.