PEP0255
Invitrogen™ Human ASK1 Synthetic Peptide
Manufacturer: Invitrogen™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PEP0255-Each-of-1 | In Stock | ₹ 16,247.84 |
PEP0255 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,247.84
GST (18%): ₹ 2,924.611
Total Price: ₹ 19,172.451
Gene ID (Entrez)
4217
Purification Method
purified
Common Name
Human ASK1
Content And Storage
-20°C
Format
Liquid
For Use With (Application)
Blocking Assay, Control
Lyophilized
No
Product Type
Peptide
Regulatory Status
RUO - research use only
Species
Human
Accession Number
Q99683
Concentration
200 μg/mL
Description
Synthetic Peptide
Formulation
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Gene Symbol
MAP3K5
Preservative
0.02% sodium azide
Quantity
50 μg
Storage Buffer
PBS
Related Products
Description
- ASK1 Synthetic Peptide, PEP-0255, from Invitrogen
- Mitogen-activated protein (MAP) kinase cascades are activated in response to various extracellular stimuli, including cytokines, growth factors and environmental stresses
- A novel MAP kinase kinase kinase (MAPKKK) was identified and designated ASK1 (for apoptosis signal-regulating kinase 1) and MAPKKK5
- ASK1 activates two different subgroups of MAPKK, MKK4 and MKK6, which in turn activates c-Jun N-terminal kinase (JNK) and p38 MAP kinase, respectively
- ASK1/MAPKKK5 is activated by TNFR and Fas through the interaction with members of the TRAF family and Fas-associated protein Daxx
- Overexpression of ASK1 induced apoptotic cell death and a catalytically inactive form of ASK1 inhibited TNF-a-induced apoptosis
- ASK1 is expressed in variety of human and mouse tissues
- This peptide corresponds to 20 amino acids near the carboxy terminus of human ASK1.PEP-0255 can be used as a blocking peptide with polyclonal antibody PA5-19880.