PEP0256

Invitrogen™ Human STAT1 Synthetic Peptide

Manufacturer: Invitrogen™

Select a Size

Pack Size SKU Availability Price
Each of 1 PEP0256-Each-of-1 In Stock ₹ 16,247.84

PEP0256 - Each of 1

₹ 16,247.84

In Stock

Quantity

1

Base Price: ₹ 16,247.84

GST (18%): ₹ 2,924.611

Total Price: ₹ 19,172.451

Gene ID (Entrez)

6772

Purification Method

purified

Common Name

Human STAT1

Content And Storage

-20°C

Format

Liquid

For Use With (Application)

Blocking Assay, Control

Lyophilized

No

Product Type

Peptide

Regulatory Status

RUO - research use only

Species

Human

Accession Number

P42224

Concentration

200 μg/mL

Description

Synthetic Peptide

Formulation

PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2

Gene Symbol

STAT1

Preservative

0.02% sodium azide

Quantity

50 μg

Storage Buffer

PBS

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Description

  • STAT1 alpha Synthetic Peptide, PEP-0256, from Invitrogen
  • STAT1 (signal transducers and activators of transcription 1) is a member of the STAT family of transcription factors
  • STAT1 can be activated by interferon-alpha, interferon-gamma, EGF, PDGF and IL6
  • STAT1 is known to regulate several genes which are involved in cell growth, apoptosis, immune responses, and lipid metabolism
  • Further, STAT1 plays an important role in mediating cell viability in response to different cell stimuli and pathogen exposure
  • The STAT1 gene is located on chromosome 2
  • STAT1 is activated to regulate gene expression in response to extracellular signaling polypeptides including cytokines, interferons, and growth factors
  • After phosphorylation by JAK tyrosine kinases, STAT1 enters the nucleus to regulate transcription of many different genes
  • Among the seven STATs types, STAT1, STAT3, STAT5a, and STAT5b have a wide activation profile
  • STAT1 is activated by many different ligands including IFN family (IFN-Alpha, IFN-Beta, IFN-gamma and IL-10), gp130 family (IL-6, IL-11, LIF, CNTF, and G-CSF), and receptor tyrosine kinases (EGF, PDGF, and CSF-1)
  • Two alternatively spliced transcript variants encoding distinct isoforms of STAT1 have been described
  • This peptide corresponds to 39 amino acids near the carboxy terminus of human STAT1 Alpha.PEP-0256 can be used as a blocking peptide with polyclonal antibody PA5-19858.