Thermo Scientific™ GeneBLAzer™ PTGDR-CRE-blaCHO-K1 Cells
Manufacturer: Thermo Scientific™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | K1739-Each-of-1 | In Stock | ₹ 8,89,824.00 |
K1739 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 8,89,824.00
GST (18%): ₹ 1,60,168.32
Total Price: ₹ 10,49,992.32
Accession Number
NM_000953.2
Cell State
Dividing Cells
Detection Method
Fluorescence
Gene Symbol
PTGDR
Product Line
GeneBLAzer™
Reporter Gene
BLA (Beta-Lactamase)
Cell Line
CHO-K1
Druggable Target
GPCR
Assay Entry
Cell-based beta lactamase reporter gene
Content And Storage
Contents:K1739 GeneBLAzer™ PTGDR-CRE-blaCHO-K1 cells(LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).Includes:• GeneBLAzer™ PTGDR-CRE-blaCHO-K1 cells• GeneBLAzer™ PTGDR-CRE-blaCHO-K1 Assay Protocol• Certificate of AnalysisStorage:The GeneBLAzer™ PTGDR-CRE-blaCHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
For Use With (Application)
FRET
Population Status
Single Cell Clone Origin
Quantity
2 x 106Cells
Target Entry
PTGDR
System Type
GeneBLAzer™
Related Products
Description
- CellSensor™ CRE- bla CHO-K1 cells (Cat
- no
- K1535) contain a beta-lactamase reporter gene under control of the Cyclic AMP Response Element (CRE) response element
- The GeneBLAzer™ PTGDR-CRE- bla CHO-K1cells are functionally validated for Z' and EC 50 concentrations of Prostaglandin D2
- In addition, GeneBLAzer™ PTGDR-CRE- bla CHO-K1 cells have been tested for assay performance under variable conditions
- These data are found in the Validation & Assay Performance Summary
- The PTGDR receptor also known as DP, is a Gs-coupled receptor which activates adenylate cyclase
- PTGDR receptors are located in vascular smooth muscle cells and blood platelets, and are also believed to be expressed in the brain, where they may be involved in the regulation of sleep
- In addition, knockout studies in mice suggest that PTGDR may be involved in allergic and asthmatic responses
- Potent agonists and antagonists for PTGDR have been identified.