K1858

Thermo Scientific™ T-REx™ Tango™ P2RY14-blaU2OS Cells

Manufacturer: Thermo Scientific™

Select a Size

Pack Size SKU Availability Price
Each of 1 K1858-Each-of-1 In Stock ₹ 9,05,224.80

K1858 - Each of 1

₹ 9,05,224.80

In Stock

Quantity

1

Base Price: ₹ 9,05,224.80

GST (18%): ₹ 1,62,940.464

Total Price: ₹ 10,68,165.264

Accession Number

NM_014879.2

Cell State

Dividing Cells

Cytoplasmic Tail

Native Tail

For Use With (Application)

FRET

Population Status

Single Cell Clone Origin

Quantity

8 x 106Cells

Reporter Gene

BLA (Beta-Lactamase)

Type

U2OS Cell

System Type

Tango™

Assay Entry

Cell-based beta-arrestin recruitment

Content And Storage

Tango™ cell lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.

Detection Method

Fluorescence

Human Protein Class

G-Protein Coupled Receptor (GPCR)

Product Line

Tango™

Readout

End Point

Target Entry

P2RY14

Cell Line

U2OS

Druggable Target

GPCR

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Description

  • T-REx™ Tango™ P2RY14-bla U2OS cells contain the human purinergic receptor P2Y14 (P2RY14) under doxycycline inducible control linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line
  • This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase reporter gene under the control of a UAS response element
  • The T-REx™ Tango™ P2RY14-bla U2OS cells have been functionally validated for Z' factor and EC50 concentrations of UDP-glucose
  • In addition, T-REx™ Tango™ P2RY14-bla U2OS cells have been tested for assay performance under variable conditions.