H6291
Interleukin-1β human
IL-1β, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture, endotoxin tested
Manufacturer: Sigma Aldrich
Synonym(S): IL-1β, Lymphocyte activating factor
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 μG | H6291-10-μG | In Stock | ₹ 54,057.00 |
H6291 - 10 μG
In Stock
Quantity
1
Base Price: ₹ 54,057.00
GST (18%): ₹ 9,730.26
Total Price: ₹ 63,787.26
biological source
human
Quality Level
100
recombinant
expressed in HEK 293 cells
Assay
≥95% (SDS-PAGE)
form
lyophilized powder
potency
≤0.05 ng/mL EC50
quality
endotoxin tested
mol wt
dimer 18-25 kDa (glycosylated)
packaging
pkg of 10 μg
technique(s)
cell culture | mammalian: suitable
Related Products
Description
- Biochem/physiol Actions: Interleukin-1 (IL-1), originally known as Lymphocyte Activating Factor (LAF), activates T cell lymphocytes, which then proliferate and secrete interleukin-2 (IL-2). IL-1 is released primarily from stimulated macrophages and monocytes, but has also been shown to be released from several other types and is thought to play a key role in inflammatory and immune responses. Other synonyms for IL-1 include: endogenous pyrogen (EP), mitogenic protein (MP), Helper Peak-1 (HP-1), T Cell Replacing Factor III (TRF III or TRFM), B Cell Activating Factor (BAF) and B Cell Differentiation Factor (BDF) The two closely related agents Interleukin-1α (IL-1α) and Interleukin-1β (IL-1β) share 62% homology in amino acid sequence and elicit nearly identical biological responses. IL-1α and IL-1β are both approximately 17 kDa with some heterogeneity in the amount of glycosylation.
- Physical form: Lyophilized from a 0.2 μm filtered solution of 1x PBS.
- Preparation Note: HumanKine Recombinant Human IL-1β, expressed in human HEK 293 cells, is a glycosylated monomer with a molecular mass of 18-25 kDa. Production in human HEK 293 cells offers authentic glycosylation. Glycosylation contributes to stability in cell growth media and other applications.
- Analysis Note: The activity is determined by the dose-dependent stimulation of the proliferation of mouse D10S cells.
- Legal Information: HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable