Colchicine
suitable for plant cell culture, BioReagent, ≥95% (HPLC)
Manufacturer: Sigma Aldrich
CAS Number: 64-86-8
Synonym(S): (S)-N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 500 MG | C3915-500-MG | In Stock | ₹ 11,398.73 |
| 1 G | C3915-1-G | In Stock | ₹ 18,813.85 |
| 5 G | C3915-5-G | In Stock | ₹ 72,191.93 |
C3915 - 500 MG
In Stock
Quantity
1
Base Price: ₹ 11,398.73
GST (18%): ₹ 2,051.771
Total Price: ₹ 13,450.501
product line
BioReagent
Quality Level
200
Assay
≥95% (HPLC)
form
powder
technique(s)
cell culture | plant: suitable
mp
150-160 °C (dec.) (lit.)
application(s)
agriculture
SMILES string
COC1=CC=C2C(=CC1=O)[C@H](CCc3cc(OC)c(OC)c(OC)c23)NC(C)=O
InChI
1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1
InChI key
IAKHMKGGTNLKSZ-INIZCTEOSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | MilliporeSigma™ Calbiochem™ Colchicine, Colchicum autumnale | -- | -- | |
| | MilliporeSigma™ Calbiochem™ Colchicine, Colchicum autumnale | -- | ₹ 9,938.65 | |
| | MilliporeSigma™ Calbiochem™ Colchicine, Colchicum autumnale | -- | ₹ 50,980.93 | |
| | Cayman Chemical Colchicine, 64-86-8, 100 mg | -- | ₹ 2,635.25 | |
| | AdipoGen Colchicine,Chemical. CAS: 64-86-8 | -- | ₹ 6,887.58 | |
| | Sigma Aldrich Fine Chemicals Biosciences Colchicine | 64-86-8 | MFCD00078484 | 100mg | -- | ₹ 4,081.21 | |
| | Medchemexpress LLC HY-16569 500mg , Colchicine CAS:64-86-8 Purity:98% | -- | ₹ 7,007.36 | |
| | AdipoGen Colchicine, 64-86-8, MFCD00078484, 100 mg | -- | ₹ 2,840.59 | |
| | Colchicine | -- | ₹ 19,452.53 | |
| | Colchicine for system suitability A | -- | ₹ 17,157.63 |
Related Products
Description
- General description: Colchicine is a tricyclic alkaloid that can stay in circulation for 20 to 40 hours post intake. Leucocytes harbour maximum colchicine.[1] It contains three hexameric rings termed A, B and C.[2]
- Application: Colchicine has been used:as an inhibitor of tubulin polymerization in bone-marrow-derived macrophages[3]for the inhibition of in vitro neurite outgrowth in human neuronal cells[4]as microtubule destabilizer to induce peripheral neuropathy in induced pluripotent stem cell derived neurons (iPSC-Neurons)[5]
- Biochem/physiol Actions: Colchicine interacts with albumin and binds to tubulin. Its association with tubulin impacts autophagic vacuole fusion with lysosomes.[1] It inhibits tyrosine kinases and phospholipases. Colchicine may be useful for treating acute coronary syndromes.[2] It is prescribed for treating rheumatologic conditions including familial mediterranean fever (FMF) and acute gouty arthritis.[6]
- Preparation Note: Preparation and Use
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 2 Oral - Muta. 1B
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves