Description

• General description: Human serum albumin (HSA) is an abundant protein found in the plasma.[1] This globular, soluble, and unglycosylated monomeric protein[2], has three homologous domains (I, II, and III).[1][3] These domains have subdomains A and B having common structural motifs. The HSA gene is located on the human chromosome 4q13.3.[3]
• Application: Albumin, Human Serum, Fraction V, Low Heavy Metals has been used:as a supplement in double buffer and milliQ-water for in vivo[4]in serum-free media for polarized secretion assays in human dermal microvascular endothelial cells[5]as a supplement in sodium phosphate buffer for the reconstitution of hormone lysis samples[6]
• Biochem/physiol Actions: Human serum albumin (HSA) is very crucial in stabilizing extracellular fluid volume. It functions as an excipient for vaccines and therapeutic protein drugs. HSA serves as a cell culture medium supplement for the synthesis of vaccines and pharmaceuticals.[2] It is useful as a carrier protein for steroids, fatty acids, and thyroid hormones.[2] HSA is used to treat cardiopulmonary bypass, trauma, hemorrhage, and hypoalbuminemia.[1] HSA is useful in biological applications, such as implantable biomaterials, biochromatography, surgical adhesives, and sealants.[1]
• Warning: Toxicity: Standard Handling (A)
• Preparation Note: Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
• Reconstitution: Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
• Legal Information: CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
• Disclaimer: RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.