44583

Doxorubicin hydrochloride

suitable for fluorescence, 98.0-102.0% (HPLC)

Manufacturer: Sigma Aldrich

CAS Number: 25316-40-9

Synonym(S): DOX, Hydroxydaunorubicin hydrochloride

Select a Size

Pack Size SKU Availability Price
1 MG 44583-1-MG In Stock ₹ 6,765.63

44583 - 1 MG

₹ 6,765.63

In Stock

Quantity

1

Base Price: ₹ 6,765.63

GST (18%): ₹ 1,217.813

Total Price: ₹ 7,983.443

biological source

synthetic

Quality Level

200

Assay

98.0-102.0% (HPLC)

form

solid

color

orange to dark red

mp

216 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL, clear, orange to redDMSO: solubleTHF: solubleethanol: solublemethanol: soluble

fluorescence

λem 580-590 nm

suitability

suitable for fluorescence

antibiotic activity spectrum

neoplastics

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Description

  • General description: Chemical structure: tetracycline
  • Application: Doxorubicin was used to induce apoptosis, and to induce cardiotoxicity in SK-N-MC cells [1][2]. It is used to inhibit macromolecular biosynthesis.
  • Biochem/physiol Actions: Doxorubicin ia an antitumor antibiotic that intercalates DNA and inhibits macromolecular biosynthesis. DNA replication is haulted due to the inhibition of topoisomerase II. It is an inhibitor of reverse transcriptase and RNA polymerase and is an immunosuppressive agent [3].
  • Packaging: Bottomless glass bottle. Contents are inside inserted fused cone.
  • Other Notes: Keep container tightly closed in a dry and well-ventilated place.

SAFETY INFORMATION

Pictograms

GHS08,GHS07

Signal Word

Danger

Hazard Statements

H302,H340,H350,H360FD

Precautionary Statements

P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405

Hazard Classifications

Acute Tox. 4 Oral - Carc. 1B - Muta. 1B - Repr. 1B

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves