869001-M
Follicle Stimulating Hormone, Human Pituitary, Iodination Grade
Follicle Stimulating Hormone, Human Pituitary, Iodination Grade, CAS 9002-68-0, is a native pituitary protein that regulates Sertoli cells by acting on G-protein-linked cell surface FSH receptors.
Manufacturer: Sigma Aldrich
CAS Number: 9002-68-0
Synonym(S): Follicle Stimulating Hormone, Human Pituitary, Iodination Grade, Follitropin, hFSH
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 μG | 869001-M-10-μG | In Stock | ₹ 22,502.14 |
| 50 μG | 869001-M-50-μG | In Stock | ₹ 62,860.00 |
869001-M - 10 μG
In Stock
Quantity
1
Base Price: ₹ 22,502.14
GST (18%): ₹ 4,050.385
Total Price: ₹ 26,552.525
biological source
human pituitary glands
Quality Level
200
sterility
non-sterile
product line
Calbiochem®
Assay
≥90%
form
lyophilized solid
specific activity
≥2000 IU/mg
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
impurities
≤0.1% hCG≤0.5% hLH, hTSH
Related Products
Description
- General description: Follicle-stimulating hormone (FSH) belongs to the family of glycoprotein hormones. It is synthesized in the gonadotrophs present in the pituitary gland.[1] FSH contains non-covalently associated α- and β-subunits and is a disulfide-rich heterodimer.[2]Research area: Cell Signaling
- Biochem/physiol Actions: Follicle-stimulating hormone (FSH) participates in the regulation of reproduction in mammals.[2] It exerts its effects through a G-protein-coupled receptor known as follicle-stimulating hormone receptor (FSHR)[2] that is located on the granulosa cells of the ovaries and Sertoli cells of the testes.[1] FSH plays a role in the maturation of ovarian follicles in females and supports spermatogenesis by activating Sertoli cell proliferation in males.[2] The interaction of FSH with its receptor FSH-R leads to the activation of G-protein coupled receptors/cyclic adenosine monophosphate (cAMP)/protein kinase A pathways to transmit intracellular signals.[3]
- Warning: Toxicity: Carcinogenic / Teratogenic (D)
- Preparation Note: Prepared from tissue of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
- Reconstitution: Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
- Other Notes: Costrici, N., et al. 1995. Endocrinology136, 4705.
- Legal Information: CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable