C1832

Cyclosporin A

from Tolypocladium inflatum, BioReagent, for molecular biology, ≥95%

Manufacturer: Sigma Aldrich

CAS Number: 59865-13-3

Synonym(S): Antibiotic S 7481F1, Cyclosporine

Select a Size

Pack Size SKU Availability Price
5 MG C1832-5-MG In Stock ₹ 32,811.60
10 MG C1832-10-MG In Stock ₹ 59,063.10

C1832 - 5 MG

₹ 32,811.60

In Stock

Quantity

1

Base Price: ₹ 32,811.60

GST (18%): ₹ 5,906.088

Total Price: ₹ 38,717.688

biological source

Tolypocladium inflatum

Quality Level

300

grade

for molecular biology

product line

BioReagent

Assay

≥95%

form

powder

technique(s)

drug transporter assay: suitable

solubility

dichloromethane: 9.80-10.20 mg/mL, clear, colorless to faintly yellow

suitability

corresponds to standard suitable for molecular biology

antibiotic activity spectrum

fungi

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Description

  • General description: Chemical structure: peptide
  • Application: Cyclosporin A was suitable for: Using in in vivo Neovascularization Assay, to subcutaneously inject the mice daily for suppressing the immune response.[1]Measuring the multiple drug resistance transporter activity in putative cancer stem/progenitor cells.[2]mRNA transcription studiesanalytical standard
  • Biochem/physiol Actions: A fungal metabolite possessing potent immunosuppressive properties. It inhibits the T-cell receptor signal transduction pathway via the formation of cyclosporin A−cyclophilin complex that inhibits calcineurin (protein phosphatase 2B). Inhibits nitric oxide synthesis induced by interleukin 1α, lipopolysaccharides and TNFα. Can block cytochrome c release from mitochondria.

SAFETY INFORMATION

Pictograms

GHS08,GHS07

Signal Word

Danger

Hazard Statements

H302,H350,H360FD

Precautionary Statements

P201 - P202 - P264 - P270 - P301 + P312 - P308 + P313

Hazard Classifications

Acute Tox. 4 Oral - Carc. 1B - Repr. 1B

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves