C1988

Cycloheximide

Biotechnology Performance Certified

Manufacturer: Sigma Aldrich

CAS Number: 66-81-9

Synonym(S): 3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide, Actidione, Naramycin A

Select a Size

Pack Size SKU Availability Price
1 G C1988-1-G In Stock ₹ 16,096.78
5 G C1988-5-G In Stock ₹ 45,340.00

C1988 - 1 G

₹ 16,096.78

In Stock

Quantity

1

Base Price: ₹ 16,096.78

GST (18%): ₹ 2,897.42

Total Price: ₹ 18,994.20

grade

Biotechnology Performance Certified

Quality Level

200

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

solubility

ethanol: 50 mg/mL

antibiotic activity spectrum

fungiyeast

Mode of action

protein synthesis | interferes

storage temp.

2-8°C

SMILES string

[H][C@]1(C[C@@H](C)C[C@H](C)C1=O)[C@H](O)CC2CC(=O)NC(=O)C2

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Description

  • Application: Cycloheximide is widely used for selection of CHX-resistant strains of yeast and fungi, controlled inhibition of protein synthesis for detection of short-lived proteins and super-induction of protein expression, and apoptosis induction or facilitation of apoptosis induction by death receptors. It has been shown to selectively clear macrophages in atherosclerotic plaques[1] and activate cumulus-free equine oocytes.[2]
  • Biochem/physiol Actions: Mode of Action: Translation inhibition in eukaryotes resulting in cell growth arrest and cell death. CHX is widely used for the selection of CHX-resistant strains of yeast and fungi, controlled inhibition of protein synthesis for detection of short-lived proteins and super-induction of protein expression, and apoptosis induction or facilitation of apoptosis induction by death receptors. Activity Spectrum: Active against yeast and fungi like Candida, Aspergillus, Saccharomyces, Penicillium
  • Other Notes: 2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

SAFETY INFORMATION

Pictograms

GHS06,GHS08,GHS09

Signal Word

Danger

Hazard Statements

H300,H341,H360D,H411

Precautionary Statements

P201 - P202 - P264 - P270 - P273 - P301 + P310

Hazard Classifications

Acute Tox. 2 Oral - Aquatic Chronic 2 - Muta. 2 - Repr. 1B

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves