Clarithromycin
≥95% (HPLC)
Manufacturer: Sigma Aldrich
CAS Number: 81103-11-9
Synonym(S): 6-O-methyl erythromycin
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 100 MG | C9742-100-MG | In Stock | ₹ 10,998.20 |
| 250 MG | C9742-250-MG | In Stock | ₹ 16,064.30 |
| 1 G | C9742-1-G | In Stock | ₹ 48,052.18 |
C9742 - 100 MG
In Stock
Quantity
1
Base Price: ₹ 10,998.20
GST (18%): ₹ 1,979.676
Total Price: ₹ 12,977.876
Quality Level
200
Assay
≥95% (HPLC)
form
powder
antibiotic activity spectrum
Gram-negative bacteriaGram-positive bacteria
Mode of action
protein synthesis | interferes
SMILES string
O[C@@H]([C@@](O)(C)[C@@H](CC)OC([C@H](C)[C@H]1O[C@@H]2O[C@@H](C)[C@H](O)[C@](C)(OC)C2)=O)[C@@H](C)C([C@H](C)C[C@@](C)(OC)[C@H](O[C@@H]3O[C@H](C)C[C@H](N(C)C)[C@H]3O)[C@H]1C)=O
InChI
1S/C38H69NO13/c1-15-26-38(10,45)31(42)21(4)28(40)19(2)17-37(9,47-14)33(52-35-29(41)25(39(11)12)16-20(3)48-35)22(5)30(23(6)34(44)50-26)51-27-18-36(8,46-13)32(43)24(7)49-27/h19-27,29-33,35,41-43,45H,15-18H2,1-14H3/t19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1
InChI key
AGOYDEPGAOXOCK-KCBOHYOISA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Sigma Aldrich Fine Chemicals Biosciences Clarithromycin European Pharmacopoeia (EP) Reference Standard | 81103-11-9 | MFCD00865140 | | -- | ₹ 23,582.90 | |
| | Clarithromycin, British Pharmacopoeia (BP) Reference Standard, MilliporeSigma™ Supelco™ | -- | ₹ 26,010.24 | |
| | Sigma Aldrich Fine Chemicals Biosciences Clarithromycin Identity United States Pharmacopeia (USP) Reference Standard | 81103-11-9 | MFCD00865140 | 10MG | -- | ₹ 1,42,354.73 | |
| | Sigma Aldrich Fine Chemicals Biosciences Clarithromycin | 81103-11-9 | MFCD00865140 | 100mg | -- | ₹ 11,634.45 | |
| | Sigma Aldrich Fine Chemicals Biosciences Clarithromycin United States Pharmacopeia (USP) Reference Standard | 81103-11-9 | MFCD00865140 | 100MG | -- | ₹ 45,791.71 | |
| | Clarithromycin | -- | ₹ 11,506.98 | |
| | Clarithromycin | -- | ₹ 16,107.60 | |
| | Clarithromycin | -- | ₹ 40,756.13 | |
| | Clarithromycin Identity | -- | ₹ 1,29,412.88 | |
| | Clarithromycin for peak identification | -- | ₹ 16,107.60 |
Related Products
Description
- General description: Chemical structure: macrolide
- Application: Clarithromycin is a semisynthetic macrolide antibiotic that is derived from erythromycin. Clarithromycin may be bacteriostatic or bactericidal depending on the organism and drug concentration . Clarithromycin may be used to attenuate cardiac transplantation rejection via matrix metalloproteinase suppression[1]. Clarithromycin has been used to study inflammatory markers in chronic obstructive pulmonary disease (COPD)[2]. It is used to study bacterial protein synthesis and peptide translation.
- Biochem/physiol Actions: Clarithromycin inhibits bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation. Clarithromycin is first metabolized to 14-OH clarithromycin, which is active and works synergistically with its parent compound. Clarithromycin penetrates the bacteria cell wall and reversibly binds to domain V of the 23S ribosomal RNA of the 50S subunit of the bacterial ribosome, blocking translocation of aminoacyl transfer-RNA and polypeptide synthesis. Clarithromycin also inhibits the hepatic microsomal CYP3A4 isoenzyme and P-glycoprotein, an energy-dependent drug efflux pump.
- Preparation Note: Practically insoluble in water, soluble in acetone and methylene chloride, slightly soluble in methanol.
- Other Notes: Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
SAFETY INFORMATION
Pictograms
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves