F0291
hBFGF
FGF-Basic, recombinant, expressed in E. coli, suitable for cell culture
Manufacturer: Sigma Aldrich
CAS Number: 106096-93-9
Synonym(S): Fibroblast Growth Factor-Basic human, FGF2, bFGF
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 25 μG | F0291-25-μG | In Stock | ₹ 52,769.40 |
F0291 - 25 μG
In Stock
Quantity
1
Base Price: ₹ 52,769.40
GST (18%): ₹ 9,498.492
Total Price: ₹ 62,267.892
biological source
human
Quality Level
200
recombinant
expressed in E. coli
Assay
≥97% (SDS-PAGE)
form
lyophilized powder
potency
≤-0.6 ng/mL
mol wt
16.0 kDa
packaging
pkg of 4X25 μgpkg of 25 μg
storage condition
avoid repeated freeze/thaw cycles
technique(s)
cell culture | mammalian: suitable
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Sigma Aldrich Fine Chemicals Biosciences Fibroblast Growth Factor-Basic Heparin Stabilized human FGF-Basic, recombinant, expressed in E. coli, sterile-filtered, aqueous solution, suitable for cell culture | 106096-93-9 | MFCD00081382 | 1ML | -- | ₹ 15,931.27 | |
| | Fibroblast Growth Factor-Basic from bovine pituitary | -- | ₹ 90,786.90 |
Related Products
Description
- General description: Fibroblast growth factor-basic (FGF-Basic) is found in basement membranes and sub-endothelial extracellular matrix. FGF-Basic is induced early in the development of the embryo where it is necessary (but not sufficient) for pluripotency and self-renewal of embryonic stem cells (ESC) and lineage defined stem cells; wherein it functions to support proliferation and inhibit differentiation. Self-renewal of hESC depends upon activation of the Activin/Nodal/Smad2,3 branch and suppression of the BMP/GDF/Smad5 branch of the TGFβ-family cell signaling program. FGF-Basic is a competence factor for Nodal support of pluripotency. Activin-A is necessary and sufficient to maintain stemness. It induces the expression of both Nodal and FGF-Basic in human ES cells.
- Application: Fibroblast growth factor-basic (FGF-Basic) is required for the maintenance of human embryonic stem cells in culture, and various other stem cell lines, such as mesenchymal stem (stroma) cells (MSC).[1][2][3]
- Physical form: Lyophilized from 0.2 μm filtered solution in 20 mM Tris and 1 M NaCl, pH 7.0, containing 50 μg bovine serum albumin per 1 μg BFGF.
- Analysis Note: The bioactivity of FGF-Basic was measured in a fluorometric assay using the redox sensitive dye, Resazurin.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves