G0282

Granulocyte-Macrophage Colony-Stimulating Factor from mouse

GM-CSF, from mouse, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Manufacturer: Sigma Aldrich

Synonym(S): GM-CSF

Select a Size

Pack Size SKU Availability Price
5 μG G0282-5-μG In Stock ₹ 35,309.10
50 μG G0282-50-μG In Stock ₹ 69,763.50

G0282 - 5 μG

₹ 35,309.10

In Stock

Quantity

1

Base Price: ₹ 35,309.10

GST (18%): ₹ 6,355.638

Total Price: ₹ 41,664.738

biological source

mouse

Quality Level

200

recombinant

expressed in E. coli

Assay

≥97% (SDS-PAGE)

form

lyophilized powder

potency

≤0.2 ng/mL EC50 (corresponds to ≥5 × 106 units/mg)

quality

endotoxin tested

mol wt

~15 kDa (125 amino acids including N-terminal methionine)

packaging

pkg of 5 and 50 μg

storage condition

avoid repeated freeze/thaw cycles

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Description

  • Biochem/physiol Actions: Granulocyte-macrophage colony stimulating factor (GM-CSF) is a growth and differentiation factor for cells in the granulocyte, macrophage and eosinophil lineage. GM-CSF stimulates colony formation from pluripotential progenitor cells at extremely low concentrations and is an essential survival and proliferative factor for hematopoietic progenitor cells in all divisions up to maturity. It also stimulates growth in some epithelial cells and osteoclasts. GM-CSF is produced by a variety of cell types (monocytes, endothelial cells, T-cells, fibroblasts, mitogen-stimulated B-cells, and LPS-stimulated macrophages). GM-CSF is secreted as a single chain glycoprotein containing 128 amino acids for human with a conserved disulfide bond. Human and murine GM-CSF share approx. 54% sequence homology and do not cross-react in bioactivity.
  • Physical form: Lyophilized from 10 mM acetic acid plus 250 μg BSA.
  • Analysis Note: The EC50 activity of mouse GM-CSF is tested in culture using murine FDP-1 cells.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves