I4032
Interleukin-21 from mouse
≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
Manufacturer: Sigma Aldrich
Synonym(S): IL-21
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 μG | I4032-10-μG | In Stock | ₹ 75,568.80 |
I4032 - 10 μG
In Stock
Quantity
1
Base Price: ₹ 75,568.80
GST (18%): ₹ 13,602.384
Total Price: ₹ 89,171.184
biological source
mouse
recombinant
expressed in E. coli
Assay
≥97% (SDS-PAGE)
form
lyophilized powder
potency
40-120 ng/mL ED50
mol wt
predicted mol wt ~14.4 kDa
packaging
pkg of 10 μg
storage condition
avoid repeated freeze/thaw cycles
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
Related Products
Description
- Biochem/physiol Actions: IL-21 (interleukin-21) belongs to the IL-2 cytokine family. It is secreted by CD4+ T, natural killer (NK) and Th17 cells. IL-21 associates with IL-21 receptor and participates in B-cell proliferation, differentiation as well as apoptosis. It also promotes the cytotoxic activity of CD8+ T cells and natural killer cells.IL-21 plays a crucial role in the differentiation of follicular helper T cells. It also exhibits antitumor activity.[1][2] It is also involved in the activation of JAK-STAT (Janus kinase - signal transducer and activator of transcription), PI3K (phosphatidylinositol 3-kinase) and MAPK (mitogen activated protein kinase) pathways.[3]
- Physical form: Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.5 mg bovine serum albumin.
- Analysis Note: The biological activity is measured by its ability to induce proliferation of human N1186 T cells.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves