I8523
Interleukin-12 from mouse
≥97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture
Manufacturer: Sigma Aldrich
Synonym(S): IL-12
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 μG | I8523-10-μG | In Stock | ₹ 57,930.90 |
I8523 - 10 μG
In Stock
Quantity
1
Base Price: ₹ 57,930.90
GST (18%): ₹ 10,427.562
Total Price: ₹ 68,358.462
biological source
mouse
Quality Level
100
recombinant
expressed in baculovirus infected Sf21 cells
Assay
≥97% (SDS-PAGE)
form
lyophilized powder
potency
0.01-.1 ng/mL ED50
mol wt
glycoprotein 70 kDa
packaging
pkg of 10 μg
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
Related Products
Description
- Application: Interleukin-12 (IL-12) from mouse has been used to study the effect of IL-12 on Th1 (type 1 T helper) immunity in Mongolian gerbils (Meriones unguiculatus) infected with Sporothrix schenckii.[1] It has been used as a standard in ELISA (enzyme-linked immunosorbent assay) cytokine assay.[2]
- Biochem/physiol Actions: Interleukin-12 (IL-12) was identified as a factor secreted by human Epstein-Barr (EBV)-transformed B cell lines. IL-12, or Natural Killer Cell Stimulatory Factor (NKSF), is a 75 kDa disulfide-linked heterodimer of a 35 kDa subunit and 40 kDa subunit. IL-12 is produced predominantly by monocytes and NK cells and induces T cells and NK cells to produce IFN-γ. Human IL-12 is not active on mouse cells, but murine IL-12 is active on both murine and human lymphocytes. The biological activity of recombinant human IL-12 was measured by its ability to stimulate the proliferation of PHA-activated human T lymphoblasts. IL-12 has anti-angiogenic properties.
- Physical form: Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.5 mg bovine serum albumin.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves