M1547

Metronidazole

BioXtra

Manufacturer: Sigma Aldrich

CAS Number: 443-48-1

Synonym(S): 2-Methyl-5-nitroimidazole-1-ethanol

Select a Size

Pack Size SKU Availability Price
5 G M1547-5-G In Stock ₹ 13,011.65
25 G M1547-25-G In Stock ₹ 17,709.70

M1547 - 5 G

₹ 13,011.65

In Stock

Quantity

1

Base Price: ₹ 13,011.65

GST (18%): ₹ 2,342.097

Total Price: ₹ 15,353.747

product line

BioXtra

Quality Level

200

impurities

≤0.0005% Phosphorus (P)≤0.1% Insoluble matter

ign. residue

≤0.1%

color

white to light yellow

mp

159-161 °C (lit.)

solubility

acetic acid: 0.1 M, clear, colorless to yellow

anion traces

chloride (Cl-): ≤0.05%sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.0005%Ca: ≤0.005%Cu: ≤0.0005%Fe: ≤0.0005%K: ≤0.005%Mg: ≤0.0005%Na: ≤0.01%Pb: ≤0.001%Zn: ≤0.0005%

antibiotic activity spectrum

Gram-negative bacteriaparasites

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Description

  • General description: Chemical structure: imidazole
  • Application: Metronidazole is used to study DNA damage and repair and has been found to induce the gene transfer agent VSH-1 in Brachyspira hyodysenteriae. It is commonly used for treatment of periodontitis and is used in bioavailability studies.
  • Biochem/physiol Actions: Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce metronidazole to its active form. Reduced metronidazole covalently binds to DNA which disrupts its helical structure, induces DNA strand breaks and inhibits bacterial nucleic acid synthesis. Bacterial cell death results.

SAFETY INFORMATION

Pictograms

GHS08

Signal Word

Danger

Hazard Statements

H340,H350,H373

Precautionary Statements

P202 - P260 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Carc. 1B - Muta. 1B - STOT RE 2

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves