420069

4,5-Dimethoxy-2-nitrobenzyl chloroformate

97%, for peptide synthesis

Manufacturer: Sigma Aldrich

CAS Number: 42855-00-5

Synonym(S): 6-Nitroveratryl chloroformate, 6-Nitroveratryloxycarbonyl chloride, NVOC chloride, NVOC-Cl

Select a Size

Pack Size SKU Availability Price
1 G 420069-1-G In Stock ₹ 13,509.60

420069 - 1 G

₹ 13,509.60

In Stock

Quantity

1

Base Price: ₹ 13,509.60

GST (18%): ₹ 2,431.728

Total Price: ₹ 15,941.328

product name

4,5-Dimethoxy-2-nitrobenzyl chloroformate, 97%

Quality Level

200

Assay

97%

form

powder

mp

125 °C (dec.) (lit.)

application(s)

peptide synthesis

storage temp.

2-8°C

SMILES string

COc1cc(COC(Cl)=O)c(cc1OC)[N+]([O-])=O

InChI

1S/C10H10ClNO6/c1-16-8-3-6(5-18-10(11)13)7(12(14)15)4-9(8)17-2/h3-4H,5H2,1-2H3

InChI key

RWWPKIOWBQFXEE-UHFFFAOYSA-N

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Description

  • Application: 4,5-Dimethoxy-2-nitrobenzyl chloroformate (NVOC-Cl) is a photolabile protecting reagent, commonly used in peptide or nucleotide synthesis to protect amines and hydroxyl groups.[1][2][3] General applications are:Preparation of inactive, caged protein conjugates which can be activated by irradiating near-ultraviolet light.[4]Solid-phase synthesis of base-sensitive S-acylthioethyl (SATE)-prooligonucleotides.[5]Modification of surface properties by introducing photocleavable NVOC moiety into chitosan to control cell attachment.[6]

SAFETY INFORMATION

Pictograms

GHS05

Signal Word

Danger

Hazard Statements

H314

Precautionary Statements

P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363

Hazard Classifications

Skin Corr. 1B

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves