77386

2-Bromo-1-ethyl-pyridinium tetrafluoroborate

≥97.0% (T)

Manufacturer: Sigma Aldrich

CAS Number: 878-23-9

Synonym(S): BEP

Select a Size

Pack Size SKU Availability Price
5 G 77386-5-G In Stock ₹ 10,889.95

77386 - 5 G

₹ 10,889.95

In Stock

Quantity

1

Base Price: ₹ 10,889.95

GST (18%): ₹ 1,960.191

Total Price: ₹ 12,850.141

Quality Level

100

Assay

≥97.0% (T)

form

crystals

reaction suitability

reaction type: Coupling Reactions

mp

103-107 °C

application(s)

peptide synthesis

SMILES string

F[B-](F)(F)F.CC[n+]1ccccc1Br

InChI

1S/C7H9BrN.BF4/c1-2-9-6-4-3-5-7(9)8;2-1(3,4)5/h3-6H,2H2,1H3;/q+1;-1

InChI key

YJDXVQLBIAJTHP-UHFFFAOYSA-N

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Description

  • General description: 2-Bromo-1-ethyl-pyridinium tetrafluoroborate is a coupling reagent employed in the synthesis of amides and esters through amidation and esterification reactions, respectively. It is generally prepared by the reaction of triethyloxonium tetrafluoroborate with 2?bromo pyridine.[1]
  • Application: 2-Bromo-1-ethyl-pyridinium tetrafluoroborate can be used as a coupling reagent for:The synthesis of N-methylated peptides in solution and solid phase.[2]The synthesis of cyclosporin A fragment and dolastatin 15 pentapeptide moiety.[3]
  • Other Notes: Coupling reagent for peptide synthesis; less racemization and faster reaction than with other reagents;e.g. BOP, PyBrOP, PyClU, BTFFH, CMBI[4]

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves