N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride
for peptide synthesis
Manufacturer: Sigma Aldrich
CAS Number: 25952-53-8
Synonym(S): N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 500 MG | 8.00907-500-MG | In Stock | ₹ 3,930.09 |
| 1 G | 8.00907-1-G | In Stock | ₹ 4,990.00 |
| 5 G | 8.00907-5-G | In Stock | ₹ 11,960.00 |
| 25 G | 8.00907-25-G | In Stock | ₹ 58,310.00 |
8.00907 - 500 MG
In Stock
Quantity
1
Base Price: ₹ 3,930.09
GST (18%): ₹ 707.416
Total Price: ₹ 4,637.506
product name
N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride, for synthesis
Quality Level
200
form
solid
reaction suitability
reaction type: Coupling Reactions
mp
110-115 °C
application(s)
peptide synthesis
storage temp.
−20°C (−15°C to −25°C)
InChI
1S/C8H17N3.ClH/c1-4-11(8-9)7-5-6-10(2)3;/h4-7H2,1-3H3;1H
InChI key
FDXPUDRRFDHONO-UHFFFAOYSA-N
Other Options
Related Products
Description
- General description: N-(3-Dimethylaminopropyl)-N-ethylcarbodiimide hydrochloride, also known as EDAC HCl or WSC, is a water-soluble condensing reagent. EDAC HCl is generally used to couple carboxylic acids with amines to form amides. The by-product urea is water-soluble and can be removed from immiscible reaction milieux by extraction with water. It is principally utilized in solution-phase peptide synthesis and as a zero-length crosslinker for protein modification.
- Application: N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride (EDC hydrochloride) can be used as:A water-soluble carbodiimide to facilitate peptide coupling reactions in alcohols.[1]A coupling agent along with HOBt to synthesize poly(glutamic acid) (PGA) polypeptides for the creation of non-fouling polypeptides that could be useful in a variety of biomedical applications.[2]A coupling reagent for the efficient synthesis of teriflunomide at the industrial scale.[3]
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
P260 - P273 - P280 - P301 + P312 - P302 + P352 + P312 - P314
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 Oral
Storage Class Code
6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable