8.52044
FMOC-Asn(Trt)-OH
N-α-Fmoc-N-ß-trityl-L-asparagine Novabiochem®
Manufacturer: Sigma Aldrich
CAS Number: 132388-59-1
Synonym(S): FMOC-Asn(Trt)-OH, N-α-Fmoc-N-β-trityl-L-asparagine
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 25 G | 8.52044-25-G | In Stock | ₹ 6,809.99 |
| 100 G | 8.52044-100-G | In Stock | ₹ 20,490.00 |
| 250 G | 8.52044-250-G | In Stock | ₹ 43,670.00 |
8.52044 - 25 G
In Stock
Quantity
1
Base Price: ₹ 6,809.99
GST (18%): ₹ 1,225.798
Total Price: ₹ 8,035.788
Quality Level
400
product line
Novabiochem®
Assay
≥98% (TLC)≥98.0% (acidimetric)≥99.0% (HPLC)
form
powder
potency
>2000 mg/kg LD50, oral (Rat)
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
mp
210-220 °C
solubility
<0.00005 g/L
application(s)
peptide synthesis
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Chem-Impex International, Inc. Na-Fmoc-Ng-trityl-L-asparagine | 132388-59-1 | MFCD00077049 | 100G | -- | ₹ 15,493.20 | |
| | Chem-Impex International, Inc. Na-Fmoc-Ng-trityl-L-asparagine | 132388-59-1 | MFCD00077049 | 250G | -- | ₹ 35,124.09 | |
| | Chem-Impex International, Inc. Na-Fmoc-Ng-trityl-L-asparagine | 132388-59-1 | MFCD00077049 | 25G | -- | ₹ 4,521.85 | |
| | Chem-Impex International, Inc. Na-Fmoc-Ng-trityl-L-asparagine | 132388-59-1 | MFCD00077049 | 5G | -- | ₹ 3,009.15 | |
| | Chemscene CS-W002327,AbaChemscene,(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-oxo-4-(tritylamino)butanoic acid,132388-59-1,100g | -- | ₹ 6,417.00 | |
| | Fmoc-Asn(Trt)-OH | -- | ₹ 8,497.63 - ₹ 1,32,725.33 | |
| | Fmoc-Asn(Trt)-OH | -- | ₹ 855.60 - ₹ 63,057.72 |
Related Products
Description
- General description: High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. Fmoc-Asn(Trt)-OH has good solubility properties in most organic solvents, and its use has been shown to result in significantly purer peptides than other derivatives used for the introduction of Asn [1,2]. Coupling can be performed by standard procedures. The trityl group is normally removed by 95% TFA in 1-3 hours, with no alkylation of Trp residues. When Asn(Trt) is the N-terminal residue, the reaction time may need to be extended to ensure complete deprotection [3]. Associated Protocols and Technical ArticlesFmoc-amino acids for Peptide ProductionCleavage and Deprotection Protocols for Fmoc SPPSLiterature references[1] P. Sieber, et al. in ′Innovation & Perspectives in Solid Phase Synthesis, 1st International Symposium′, R. Epton (Eds), SPCC UK Ltd., Birmingham, 1990, pp. 577. [2] P. Sieber, et al. (1991) Tetrahedron Lett., 32, 739. [3] M. Friede, et al. (1992) Pept. Res., 5, 145.
- Application: Synthesis of a burkholdine analogue containing β-hydroxytyrosine: This study discusses the synthesis of a burkholdine analogue, utilizing Fmoc-Asn(Trt)-OH as part of the solid support loading process (Kato et al., 2019).
- Linkage: Replaces: 04-12-1089
- Analysis Note: Colour (visual): white to off whiteAppearance of substance (visual): powderColour index (0,5 M in DMF): ≤ 150 HazenIdentity (IR): passes testEnantiomeric purity: ≥ 99.7 % (a/a)Purity (HPLC): ≥ 99.0 % (a/a)Fmoc-ß-Ala-OH (HPLC): ≤ 0.1 % (a/a)Fmoc-ß-Ala-Asn (Trt)-OH (HPLC): ≤ 0.1 % (a/a)Fmoc-Asn(Trt)-Asn(Trt)-OH (HPLC): ≤ 0.1 % (a/a)Fmoc-Asn-OH (HPLC): ≤ 0.1 % (a/a)Assay free amino acid (GC): ≤ 0.2 %Purity (TLC(011A)): ≥ 98 %Purity (TLC(0811)): ≥ 98 %Solubility (25 mmole in 50 ml DMF): clearly solubleAssay (acidimetric): ≥ 98.0 %Water (K. F.): ≤ 2.0 %Ethyl acetate (HS-GC): ≤ 0.5 %Acetate (IC): ≤ 0.05 %To see the solvent systems used for TLC of Novabiochem® products please click here.
- Legal Information: Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFETY INFORMATION
Pictograms
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable