8.52065

Fmoc-Lys(Mtt)-OH

≥98.0% (HPLC), for peptide synthesis, Novabiochem®

Manufacturer: Sigma Aldrich

CAS Number: 167393-62-6

Synonym(S): Fmoc-Lys(Mtt)-OH, N-α-Fmoc-N-ε-4-methyltrityl-L-lysine

Select a Size

Pack Size SKU Availability Price
1 G 8.52065-1-G In Stock ₹ 4,700.50
5 G 8.52065-5-G In Stock ₹ 18,440.00
25 G 8.52065-25-G In Stock ₹ 80,080.01
8520650100 8.52065-8520650100 In Stock ₹ 1,94,290.00
8520651000 8.52065-8520651000 In Stock ₹ 13,48,910.01

8.52065 - 1 G

₹ 4,700.50

In Stock

Quantity

1

Base Price: ₹ 4,700.50

GST (18%): ₹ 846.09

Total Price: ₹ 5,546.59

product name

Fmoc-Lys(Mtt)-OH, Novabiochem®

Quality Level

200

product line

Novabiochem®

Assay

≥95.0% (acidimetric)≥98% (TLC)≥98.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

mp

140-150 °C

application(s)

peptide synthesis

functional group

amine

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Description

  • General description: The side-chain Mtt group can be selectively removed with 1% TFA in DCM [1,2,3] or DCM/HFIP/TFE/TES (6.5:2:1:0.5) [4], making this an excellent derivative for the synthesis by Fmoc SPPS of branched peptides, peptides modified at the lysine side-chain [5,6], for the construction of templates and multifunctionalized resins for combinatorial synthesis. Associated Protocols and Technical ArticlesCleavage and Deprotection Protocols for Fmoc SPPSLiterature references[1] K. Barlos, et al., C. H. Schneider & A. N. Eberle (Eds), ESCOM, Leiden, 1993, pp. 283. [2] A. Aletras, et al. (1995) Int. J. Peptide Protein Res., 45, 488. [3] L. Bourel, et al. (2000) J. Peptide Sci., 6, 264. [4] K. Barlos, personal communication. [5] P. Hoogerhout, et al. (1999) J. Peptide Res., 54, 436. [6] C. Park & K. Burgess (2001) J. Comb. Chem., 3, 257.
  • Application: Synthesis of peptide-immobilized magnetic beads, and peptide reactivity assay for assessing skin sensitization utilizing chromophore . This article involves the use of Fmoc-Lys(Mtt)-OH in the creation of peptide-immobilized magnetic beads, offering insights into their potential for biomedical applications (H Miyazaki et al., 2020, Processes).
  • Linkage: Replaces: 04-12-1137
  • Analysis Note: Color (visual): white to slight yellow to beigeAppearance of substance (visual): powderIdentity (IR): passes testEnantiomeric purity: ≥ 99.5 % (a/a)Purity (TLC(0811)): ≥ 98 %Assay (HPLC, area%): ≥ 98.0 % (a/a)Solubility (1 mmole in 2 ml DMF): clearly solubleAssay (acidimetric): ≥ 95.0 %Water (K. F.): ≤ 1.0 %To see the solvent systems used for TLC of Novabiochem® products please click here.
  • Legal Information: Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFETY INFORMATION

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable