8.52067
Fmoc-Arg(Pbf)-OH
Novabiochem®
Manufacturer: Sigma Aldrich
CAS Number: 154445-77-9
Synonym(S): Fmoc-Arg(Pbf)-OH, N-α-Fmoc-N G-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 G | 8.52067-5-G | In Stock | ₹ 4,720.11 |
| 25 G | 8.52067-25-G | In Stock | ₹ 20,680.00 |
| 100 G | 8.52067-100-G | In Stock | ₹ 44,079.99 |
| 250 G | 8.52067-250-G | In Stock | ₹ 1,10,010.00 |
| 8520670500 | 8.52067-8520670500 | In Stock | ₹ 1,55,910.00 |
| 1 KG | 8.52067-1-KG | In Stock | ₹ 2,32,090.00 |
| 8520672000 | 8.52067-8520672000 | In Stock | ₹ 4,52,080.00 |
| 5 KG | 8.52067-5-KG | In Stock | ₹ 10,53,060.01 |
8.52067 - 5 G
In Stock
Quantity
1
Base Price: ₹ 4,720.11
GST (18%): ₹ 849.62
Total Price: ₹ 5,569.73
Quality Level
400
product line
Novabiochem®
Assay
≥98% (TLC)≥99.0% (HPLC)
form
powder
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
mp
>65 °C
application(s)
peptide synthesis
functional group
Fmoc
storage temp.
-10 to -25°C
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Chemscene CS-W019715,AbaChemscene,Fmoc-Arg(Pbf)-OH,154445-77-9,100g | -- | ₹ 8,213.76 | |
| | eMolecules Ambeed / Fmoc-Arg(Pbf)-OH / 10g / 552541121 / A116775 / / 154445-77-9 / MFCD00235804 / 648.780 / C34H40N4O7S | -- | ₹ 2,591.61 | |
| | Apexbio Technology LLC Fmoc-Arg(Pbf)-OH,25g CAS# 154445-77-9 | -- | ₹ 8,556.00 | |
| | Protein Technologies Inc Fmoc-Arg(Pbf)-OH | 154445-77-9 | 648.8 g/mol | 1KG | -- | ₹ 2,35,238.66 | |
| | Sigma Aldrich Fine Chemicals Biosciences Fmoc-Arg(Pbf)-OH >=98.0% (HPLC) | 154445-77-9 | MFCD00235804 | 100G | -- | ₹ 75,720.60 | |
| | Sigma Aldrich Fine Chemicals Biosciences Fmoc-Arg(Pbf)-OH >=98.0% (HPLC) | 154445-77-9 | MFCD00235804 | 5G | -- | ₹ 10,690.72 | |
| | Sigma Aldrich Fine Chemicals Biosciences Fmoc-Arg(Pbf)-OH >=98.0% (HPLC) | 154445-77-9 | MFCD00235804 | 25G | -- | ₹ 20,648.19 | |
| | Fmoc-Arg(Pbf)-OH | -- | ₹ 14,180.75 - ₹ 2,74,543.65 | |
| | Fmoc-Arg(Pbf)-OH | -- | ₹ 598.92 - ₹ 80,340.84 | |
| | 154445-77-9 | Fmoc-Arg(Pbf)-OH | -- | ₹ 427.80 - ₹ 28,063.68 |
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Description
- General description: High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. The standard derivative for the introduction of Arg in Fmoc SPPS [1,2]. The Pbf side-chain protecting group is removed with TFA approximately 1-2 times faster than Pmc.In the preparation of peptides containing both Arg and Trp, it is recommended that this derivative is used in conjunction with Fmoc-Trp(Boc)-OH (852050). Associated Protocols and Technical ArticlesFmoc-amino acids for Peptide ProductionCleavage and Deprotection Protocols for Fmoc SPPSLiterature references[1] L. A. Carpino, et al. (1993) Tetrahedron Lett., 34, 7829. [2] C. G. Fields, et al. (1993) Tetrahedron Lett., 34, 6661.
- Application: Syntheses of cyanophycin segments for investigations of cell-penetration: Describes the synthesis process and overall yields for steps from Fmoc-Arg(Pbf)-OH to Adp building blocks. (M Grogg, D Hilvert, D Seebach, 2019). Revisiting NO2 as Protecting Group of Arginine in Solid-Phase Peptide Synthesis: Compares the stability of Fmoc-Arg(Boc) 2 -OH with Fmoc-Arg(Pbf)-OH in solvents over time. (M Alhassan, A Kumar, J Lopez, F Albericio, 2020). Gene delivery of PAMAM dendrimer conjugated with the nuclear localization signal peptide originated from fibroblast growth factor 3: Discusses a conjugation reaction involving Fmoc-Arg(pbf)-OH in gene delivery systems. (J Lee, J Jung, YJ Kim, E Lee, JS Choi, 2014).
- Linkage: Replaces: 04-12-1145
- Analysis Note: Colour (visual): white to off whiteAppearance of substance (visual): powderColour index (0,5 M in DMF): ≤ 150 HazenIdentity (IR): passes testEnantiomeric purity: ≥ 99.8 % (a/a)Purity (HPLC): ≥ 99.0 % (a/a)Fmoc-ß-Ala-OH (HPLC): ≤ 0.1 % (a/a)Fmoc-ß-Ala-Arg(Pbf)-OH (HPLC): ≤ 0.1 % (a/a)Fmoc-Arg(Pbf)-Arg(Pbf)-OH (HPLC): ≤ 0.1 % (a/a)Fmoc-Arg-OH (HPLC): ≤ 0.1 % (a/a)Assay free amino acid (HPLC): ≤ 0.2 %Purity (TLC(011C)): ≥ 98 %Purity (TLC(157B)): ≥ 98 %Solubility (12,5 mmol in 25 ml DMF): clearly solubleAssay (acidimetric): ≥ 90.0 %Water (K. F.): ≤ 2.0 %Ethyl acetate (HS-GC): ≤ 1.0 %Acetate (IC): ≤ 0.02 %To see the solvent systems used for TLC of Novabiochem® products please click here.
- Legal Information: Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFETY INFORMATION
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable