8.54000
Dde-Lys(Fmoc)-OH
Novabiochem®
Manufacturer: Sigma Aldrich
CAS Number: 156648-40-7
Synonym(S): Dde-Lys(Fmoc)-OH, N-α-1-(4,4-Dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-N-ε-Fmoc-L-lysine
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 G | 8.54000-1-G | In Stock | ₹ 21,020.00 |
| 5 G | 8.54000-5-G | In Stock | ₹ 83,510.00 |
8.54000 - 1 G
In Stock
Quantity
1
Base Price: ₹ 21,020.00
GST (18%): ₹ 3,783.60
Total Price: ₹ 24,803.60
Quality Level
200
product line
Novabiochem®
Assay
≥90.0% (acidimetric)≥96.0% (HPLC)≥97% (TLC)
form
powder
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
mp
>70 °C (decomposition)
application(s)
peptide synthesis
functional group
amine
storage temp.
15-25°C
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | L-Lysine, N2-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]-N6-[(9H-fluoren-9-ylmethoxy)carbonyl]- | -- | ₹ 598.92 - ₹ 61,260.96 | |
| | Dde-Lys(Fmoc)-OH | -- | ₹ 1,796.76 - ₹ 1,21,238.52 | |
| | 156648-40-7 | Dde-Lys(Fmoc)-OH | -- | ₹ 1,197.84 - ₹ 1,05,067.68 |
Related Products
Description
- General description: Quasi-orthogonally-protected Lys derivative. The Fmoc group can be removed selectively by treatment with piperidine; the Dde group is cleaved with 2% hydrazine in DMF [1]. When removing Dde in the presence of allyl-based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group [2]. Also available Fmoc-Lys(Dde)-OH 852057. This derivative has been employed in Fmoc SPPS to facilitate the introduction of biotin to the side-chain of lysine [3]. Associated Protocols and Technical Articles Guide to Selection of Orthogonally-Protected Building Blocks for Fmoc SPPS Literature references [1] B. W. Bycroft, et al. (1993) J. Chem. Soc., Chem. Commun., 778. [2] B. Rohwedder, et al. (1998) Tetrahedron Lett., 39, 1175. [3] J. Mack, et al. (1999) Lett. Pept. Sci., 6, 135.
- Linkage: Replaces: 04-12-5201
- Analysis Note: Colour (visual): white to slight yellow to beigeAppearance of substance (visual): powderIdentity (IR): passes testEnantiomeric purity: ≥ 99.5 % (a/a)Purity (TLC(157B)): ≥ 97 %Purity (TLC(CMA2)): ≥ 97 %Assay (HPLC, area%): ≥ 96.0 % (a/a)Solubility (1 mmole in 2 ml DMF): clearly solubleAssay (acidimetric): ≥ 90.0 %Water (K. F.): ≤ 1.00 %To see the solvent systems used for TLC of Novabiochem® products please click here.
- Legal Information: Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFETY INFORMATION
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable