Guanidine hydrochloride
BioUltra, for molecular biology, ≥99.5% (AT)
Manufacturer: Sigma Aldrich
CAS Number: 50-01-1
Synonym(S): Aminoformamidine hydrochloride, Aminomethanamidine hydrochloride, Guanidinium chloride
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 50 G | 50933-50-G | In Stock | ₹ 26,467.13 |
| 250 G | 50933-250-G | In Stock | ₹ 72,722.35 |
| 1 KG | 50933-1-KG | In Stock | ₹ 1,69,898.38 |
50933 - 50 G
In Stock
Quantity
1
Base Price: ₹ 26,467.13
GST (18%): ₹ 4,764.083
Total Price: ₹ 31,231.213
biological source
synthetic
Quality Level
200
grade
for molecular biology
product line
BioUltra
Assay
≥99.5% (AT)
form
powder or crystals
technique(s)
RNA extraction: suitable
impurities
DNases, none detected RNases, none detected insoluble matter, passes filter test phosphatases, none detected proteases, none detected
ign. residue
≤0.05% (as SO4)
loss
≤0.05% loss on drying, 20 °C (HV)
Other Options
Description
- General description: Guanidine hydrochloride (GdnHCl) is a well-known protein and enzyme denaturant.[1][2] It is a small molecule and hydroscopic in nature.[1][1]
- Application: Guanidine hydrochloride (GdnHCl) has been used as a component of the phosphate buffer saline (PBS) for the incubation of Schlemm′s canal (SC) cells.[3] It has also been used as a component of the digestion buffer for the gelation and expansion of human HeLa229 cells.[4] GdnHCl is also used to isolate RNA.[5]
- Biochem/physiol Actions: Guanidine hydrochloride (GdnHCl) is involved in conformational changes and loss of enzyme activity due to inactivation of the enzyme.[2] It is involved in the loss of activity of alkaline phosphatase (ALPase) enzyme in Haliotis diversicolor.[2] GdnHCl functions by hampering the activity of heat shock protein 104 (Hsp104) adenosine triphosphatase (ATPase) in vivo.[6] It can also inactivate enzymes like papain and aminocyclase.[1] Higher concentrations of GdnHCl leads to viral inactivation of herpes simplex virus 1 (HSV-1).[7]
SAFETY INFORMATION
Pictograms
Signal Word
Warning
Hazard Statements
Precautionary Statements
P261 - P264 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338
Hazard Classifications
Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves