870606P
POVPC
Manufacturer: Sigma Aldrich
CAS Number: 121324-31-0
Synonym(S): 1-palmitoyl-2-(5′-oxo-valeroyl)-sn-glycero-3-phosphocholine
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 MG | 870606P-1-MG | In Stock | ₹ 19,160.25 |
870606P - 1 MG
In Stock
Quantity
1
Base Price: ₹ 19,160.25
GST (18%): ₹ 3,448.845
Total Price: ₹ 22,609.095
form
powder
packaging
pkg of 1 × 1 mg (870606P-1mg)
manufacturer/tradename
Avanti Polar Lipids 870606P
lipid type
phosphoglyceridesphospholipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCC([H])=O)=O)COC(CCCCCCCCCCCCCCC)=O)=O
InChI
1S/C29H56NO9P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-20-28(32)36-25-27(39-29(33)21-18-19-23-31)26-38-40(34,35)37-24-22-30(2,3)4/h23,27H,5-22,24-26H2,1-4H3/t27-/m1/s1
InChI key
RKIDALSACBQVTN-HHHXNRCGSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | 121324-31-0 | POV-PC | -- | ₹ 7,272.60 - ₹ 1,24,233.12 |
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Description
- General description: 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine (POVPC) is a derivative of oxidized Low density lipoprotein (oxLDL), a proinflammatory lipid present in atherosclerotic lesions.[1]
- Application: 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine (POVPC) has been used:to study its effects on endothelial function and vasodilation[1]as a ligand for LRP6 in bone marrow mesenchymal stromal cells (MSCs)[2]as a oxidized lipid to study if membrane status at different degrees of lipid peroxidation is involved in oxidative stress tolerance[3]
- Biochem/physiol Actions: 1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine (POVPC) affects endothelial function by hindering activity of endothelial nitric oxide synthase and stimulating endothelial cell apoptosis. It is implicated in the development of atherosclerosis and it may be used as a potent therapeutic for atherosclerosis.[1]
- Packaging: 5 mL Clear Glass Sealed Ampule (870606P-1mg)