Adenosine 5′-[γ-thio]triphosphate tetralithium salt
≥75% (HPLC), powder
Manufacturer: Sigma Aldrich
CAS Number: 93839-89-5
Synonym(S): ATP-γ-S, Adenosine 5′-(3-thiotriphosphate) tetralithium salt, Ado-5′-PPP[S]
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 1 MG | A1388-1-MG | In Stock | ₹ 13,065.78 |
| 5 MG | A1388-5-MG | In Stock | ₹ 31,197.65 |
| 25 MG | A1388-25-MG | In Stock | ₹ 77,171.43 |
A1388 - 1 MG
In Stock
Quantity
1
Base Price: ₹ 13,065.78
GST (18%): ₹ 2,351.84
Total Price: ₹ 15,417.62
biological source
synthetic (organic)
Quality Level
200
Assay
≥75% (HPLC)
form
powder
color
off-white
solubility
H2O: 25 mg/mL
shipped in
dry ice
storage temp.
−20°C
SMILES string
[Li+].[Li+].[Li+].[Li+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=S)[C@@H](O)[C@H]3O
InChI
1S/C10H16N5O12P3S.4Li/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(25-10)1-24-28(18,19)26-29(20,21)27-30(22,23)31;;;;/h2-4,6-7,10,16-17H,1H2,(H,18,19)(H,20,21)(H2,11,12,13)(H2,22,23,31);;;;/q;4*+1/p-4/t4-,6-,7-,10-;;;;/m1..../s1
Other Options
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Description
- Application: Adenosine 5′-[γ-thio]triphosphate tetralithium salt has been used to treat the pollen grains to determine the inhibitory effect of adenosine triphosphate (ATP) or its hydrolysis product.[1] It has also been used to select thiophosphorylate target protein.[2]
- Biochem/physiol Actions: Adenosine 5′-[γ-thio]triphosphate (ATP-γ-S) is widely used as a non-hydrolyzed ATP analogue for studies on the effects of ATP binding to ATP sites in a wide range of processes including extracellular functions. ATP- γ-S is a P2 purinergic agonist which increases the activity of Ca2+-activated K+ channels. ATP- γ-S can substitute for ATP in kinase reactions yielding thiophosphorylated proteins that are resistant to protein phosphatases and modulate the ATP-dependent steps in the binding of ubiquitin conjugates to the 26S proteasome. ATP-γ -S differentially modulates Toll-like receptor 4-mediated cell survival and death.
- Other Notes: Non-hydrolyzable ATP analog
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves