A211000

DMT-2′O-TBDMS-rA(bz) Phosphoramidite

Manufacturer: Sigma Aldrich

CAS Number: 104992-55-4

Synonym(S): DMT-2’O-TBDMS-rA(bz) Amidite, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1-dimethylethyl)dimethylsilyl]-adenosine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

Select a Size

Pack Size SKU Availability Price
100 G A211000-100-G In Stock ₹ 8,79,022.48
500 G A211000-500-G In Stock ₹ 39,11,483.85

A211000 - 100 G

₹ 8,79,022.48

In Stock

Quantity

1

Base Price: ₹ 8,79,022.48

GST (18%): ₹ 1,58,224.046

Total Price: ₹ 10,37,246.526

biological source

non-animal source (no BSE/TSE risk)

Quality Level

300

product line

Proligo Reagents

Assay

≥99% (31P-NMR)≥99.0% (reversed phase HPLC)

form

powder

technique(s)

oligo synthesis: suitable

impurities

≤0.3 wt. % water content (Karl Fischer)≤0.5% P(III) Impurities 100-169ppm (31P-NMR)≤0.5% single Impurity (reversed phase HPLC)≤3 wt. % residual Solvent content

color

white to off-white

λ

conforms (UV/VIS Identity)

suitability

conforms to structure for H-NMRconforms to structure for LC-MS

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Description

  • General description: DMT-2′O-TBDMS-rA(bz) Phosphoramidite belongs to the group of 2′O-TBDMS RNA Phosphoramidites.
  • Application: RNA interference (RNAi) has become a popular tool for the sequence-specific inhibition of gene expression and can be used in target validation and other drug development techniques. The most convenient method to provide sequence-specific RNA oligonucleotides is a chemical synthesis on a solid support with RNA phosphoramidites and RNA CPG, analogous to DNA synthesis.
  • Features and Benefits: Industry standard 2′O-TBDMS protective group Consistent lot-to-lot purity and performance Compatible with deprotection methods based on methylamine or AMA Standard RNA phosphoramidites provide excellent coupling results when used with ETT or BTT as activator; best results are obtained with Activator 42Capping with standard acetic anhydride capping reagent rather than with Fast Deprotection Cap A Manufactured under a certified ISO 9001 quality system
  • Other Notes: The unique properties of RNA have stimulated the development of a variety of applications in diagnostics and therapeutics, as well as in basic molecular biology research where RNA can be used as: Catalytic agents (ribozymes) Affinity ligands (aptamers) Agents to induce gene silencing (RNA interference)

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable