A4882
6-Thioguanine
≥98%
Manufacturer: Sigma Aldrich
CAS Number: 154-42-7
Synonym(S): 2-Amino-6-mercaptopurine, 2-Amino-6-purinethiol
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 100 MG | A4882-100-MG | In Stock | ₹ 3,390.00 |
| 250 MG | A4882-250-MG | In Stock | ₹ 6,726.60 |
| 500 MG | A4882-500-MG | In Stock | ₹ 8,114.10 |
| 1 G | A4882-1-G | In Stock | ₹ 8,720.00 |
| 5 G | A4882-5-G | In Stock | ₹ 40,392.90 |
A4882 - 100 MG
In Stock
Quantity
1
Base Price: ₹ 3,390.00
GST (18%): ₹ 610.20
Total Price: ₹ 4,000.20
Quality Level
200
Assay
≥98%
form
powder
mp
≥300 °C (lit.)
SMILES string
NC1=Nc2nc[nH]c2C(=S)N1
InChI
1S/C5H5N5S/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)
InChI key
WYWHKKSPHMUBEB-UHFFFAOYSA-N
Gene Information
human ... IMPDH1(3614) , IMPDH2(3615)
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Selleck Chemical LLC Thioguanine 50mg 154-42-7 | -- | ₹ 9,959.18 | |
| | Selleck Chemical LLC Thioguanine 500mg 154-42-7 | -- | ₹ 30,493.58 | |
| | Sigma Aldrich Fine Chemicals Biosciences Thioguanine United States Pharmacopeia (USP) Reference Standard | 154-42-7 | MFCD00233553 | 200MG | -- | ₹ 43,224.91 | |
| | Sigma Aldrich Fine Chemicals Biosciences 6-Thioguanine | 154-42-7 | MFCD00233553 | 100mg | -- | ₹ 6,322.88 | |
| | Sigma Aldrich Fine Chemicals Biosciences 6-Thioguanine >=98% | 154-42-7 | MFCD00233553 | 500MG | -- | ₹ 12,892.18 | |
| | Sigma Aldrich Fine Chemicals Biosciences 6-Thioguanine >=98% | 154-42-7 | MFCD00233553 | 250MG | -- | ₹ 7,974.19 | |
| | Thioguanine | -- | ₹ 19,469.40 | |
| | Tioguanine | -- | ₹ 24,553.20 | |
| | 6-Thioguanine | -- | ₹ 2,786.10 | |
| | 6-Thioguanine | -- | ₹ 1,026.72 - ₹ 32,769.48 |
Related Products
Description
- General description: 6-Thioguanine is a variant of guanine with hydrogen bonding at the N-7 of the purine ring. Its association with cytosine alters the dimension of the base stacking.[1] 6-Thioguanine usage in treating inflammatory bowel disease (IBD) contributes to nodular regenerative hyperplasia (NRH) in the liver.[2]
- Application: 6-Thioguanine has been used:to induce autophagy and apoptosis in colorectal cancer cell lines HCT116[3]as a selection marker in the mutation and survival assay in chinese hamster lung fibroblasts culture V79[4]as a selection marker in clonogenic Lung metastasis assay of 4T1-luc cells[5]
- Biochem/physiol Actions: Ribosylated and phosphorylated by the same pathway as natural purine bases; as the nucleotide, inhibits a variety of cellular processes involved in nucleic acid synthesis. Has a long history as an effective treatment of leukemia.
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Oral
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves