B5002

5-Bromo-2′-deoxyuridine

≥99% (HPLC)

Manufacturer: Sigma Aldrich

CAS Number: 59-14-3

Synonym(S): 5-BrdU, 5-Bromo-1-(2-deoxy-β-D-ribofuranosyl)uracil, 5-Bromouracil deoxyriboside, BUdR

Select a Size

Pack Size SKU Availability Price
100 MG B5002-100-MG In Stock ₹ 6,906.35
250 MG B5002-250-MG In Stock ₹ 8,724.95
500 MG B5002-500-MG In Stock ₹ 13,238.98
1 G B5002-1-G In Stock ₹ 16,215.85
5 G B5002-5-G In Stock ₹ 64,657.73
100 G B5002-100-G In Stock ₹ 9,74,877.85

B5002 - 100 MG

₹ 6,906.35

In Stock

Quantity

1

Base Price: ₹ 6,906.35

GST (18%): ₹ 1,243.143

Total Price: ₹ 8,149.493

biological source

synthetic (organic)

Quality Level

200

Assay

≥99% (HPLC)

form

powder

mp

191-194 °C (dec.) (lit.)

solubility

DMSO: 50 mg/mL, clear, colorless to very faintly yellow

storage temp.

−20°C

SMILES string

OC[C@H]1O[C@H](C[C@@H]1O)N2C=C(Br)C(=O)NC2=O

InChI

1S/C9H11BrN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1

InChI key

WOVKYSAHUYNSMH-RRKCRQDMSA-N

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Description

  • Application: 5-Bromo-2′-deoxyuridine (5-BrdU) is a thymidine analogue which is incorporated into DNA. 5-BrdU is routinely and extensively used to measure DNA synthesis and to label dividing cells. Consequently 5-BrdU is used to study cell signaling and other processes that induce cell proliferation.
  • Biochem/physiol Actions: 5-Bromo-2′-deoxyuridine (BrdU) is used to analyze cell proliferation,[3] because of its facile incorporation into DNA during the S phase of the cell cycle. BrdU stimulates cellular differentiation and maturation in leukemia cell lines, while it inhibits differentiation of friend erythroleukemia cells.[4] Studies of BrdU incorporation often subsequently use BrdU-specific antibodies with fluorescent tags, for detection of the incorporated BrdU, via such methods as flow cytometry or fluorescence microscopy.

SAFETY INFORMATION

Pictograms

GHS08

Signal Word

Danger

Hazard Statements

H340,H361fd

Precautionary Statements

P201 - P202 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Muta. 1B - Repr. 2

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves