C6013

Cholesteryl hemisuccinate tris salt

anionic detergent

Manufacturer: Sigma Aldrich

CAS Number: 102601-49-0

Synonym(S): 3β-Hydroxy-5-cholestene 3-hemisuccinate, 5-Cholesten-3β-ol 3-hemisuccinate, CHEMS, CHS, Cholesteryl hydrogen succinate

Select a Size

Pack Size SKU Availability Price
5 G C6013-5-G In Stock ₹ 64,300.50
25 G C6013-25-G In Stock ₹ 1,83,721.90

C6013 - 5 G

₹ 64,300.50

In Stock

Quantity

1

Base Price: ₹ 64,300.50

GST (18%): ₹ 11,574.09

Total Price: ₹ 75,874.59

biological source

synthetic (organic)

Quality Level

200

Assay

≥98% (TLC)

form

powder

functional group

ester

shipped in

ambient

storage temp.

−20°C

SMILES string

NC(CO)(CO)CO.CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@H](CC[C@]4(C)[C@H]3CC[C@]12C)OC(=O)CCC(O)=O

InChI

1S/C31H50O4.C4H11NO3/c1-20(2)7-6-8-21(3)25-11-12-26-24-10-9-22-19-23(35-29(34)14-13-28(32)33)15-17-30(22,4)27(24)16-18-31(25,26)5;5-4(1-6,2-7)3-8/h9,20-21,23-27H,6-8,10-19H2,1-5H3,(H,32,33);6-8H,1-3,5H2/t21-,23+,24+,25-,26+,27+,30+,31-;/m1./s1

InChI key

SLDYONDUXRBLLR-XTCKSVDZSA-N

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Description

  • Application: Cholesteryl hemisuccinate tris salt has been used:to prepare solubilization buffer for glucan synthase assay[1]to prepare immunoprecipitation buffer for immobilization of opioid receptors on paramagnetic beads.[2]as a membrane stabilizer for liposomes[3] and protein synaptogyrin-1[4] as a component of a folate-modified self-microemulsifying drug delivery system.[5] with N-dodecyl β-D-maltoside (DDM) to solubilize erythrocyte ghosts[6] and chemokine receptor CCR1[7]for protein solubilization
  • Biochem/physiol Actions: Cholesteryl hemisuccinate is an ionizable anionic detergent that stabilizes large unilamellar vesicles. These liposome vesicles act as delivery agents for anticancer drugs, oligonucleotides and antibiotics.[8][9] Cholesteryl succinate also reportedly exhibits antiproliferative activity and may be clinically useful as antitumor agent.[10]
  • Preparation Note: Cholesteryl hemisuccinate tris salt yields clear, colorless solution in methanol at 10 mg/ml.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable