M1762

Methylmalonyl coenzyme A tetralithium salt hydrate

≥90% (HPLC)

Manufacturer: Sigma Aldrich

CAS Number: 104809-02-1

Synonym(S): α-Methylmalonyl coenzyme A tetralithium salt, MM-CoA

Select a Size

Pack Size SKU Availability Price
1 MG M1762-1-MG In Stock ₹ 13,401.35
5 MG M1762-5-MG In Stock ₹ 44,469.10
25 MG M1762-25-MG In Stock ₹ 1,75,137.68

M1762 - 1 MG

₹ 13,401.35

In Stock

Quantity

1

Base Price: ₹ 13,401.35

GST (18%): ₹ 2,412.243

Total Price: ₹ 15,813.593

Quality Level

200

Assay

≥90% (HPLC)

storage temp.

−20°C

SMILES string

[Li+].[Li+].[Li+].[Li+].O.CC(C([O-])=O)C(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)([O-])=O)n2cnc3c(N)ncnc23

InChI

1S/C25H40N7O19P3S.4Li.H2O/c1-12(23(37)38)24(39)55-7-6-27-14(33)4-5-28-21(36)18(35)25(2,3)9-48-54(45,46)51-53(43,44)47-8-13-17(50-52(40,41)42)16(34)22(49-13)32-11-31-15-19(26)29-10-30-20(15)32;;;;;/h10-13,16-18,22,34-35H,4-9H2,1-3H3,(H,27,33)(H,28,36)(H,37,38)(H,43,44)(H,45,46)(H2,26,29,30)(H2,40,41,42);;;;;1H2/q;4*+1;/p-4/t12?,13-,16-,17-,18+,22-;;;;;/m1...../s1

InChI key

ANDKBBZIPFWODN-WLVKLPLXSA-J

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Description

  • Application: Coenzyme A functions as an acyl group carrier, acetyl-CoA. Methylmalonyl coenzyme A (MM-CoA) is a substrate used to study the specificity and kinetics of enzymes such as methylmalonyl Coenzyme A mutase (succinyl-Ca forming), methylmalonyl-CoA decarboxylase (EC 4.1.1.41), and methylmalonyl-CoA hydrolase (EC 3.1.2.17).
  • Biochem/physiol Actions: Methylmalonyl coenzyme A (CoA) is a catabolite of odd-chain fatty acids, cholesterol and few amino acids like valine, isoleucine, methionine, threonine.[1][2] It is produced by the activity of the enzyme propionyl-CoA carboxylase(PCC).[2] Methylmalonyl coenzyme A (CoA) is converted to succinyl-CoA by the methylmalonyl-CoA mutase (MCM) and vitamin B12 as the cofactor. Either a low MCM activity or an altered metabolism of vitamin B12 causes the inherited metabolic disease methylmalonic acidemia (MMA).[1]

SAFETY INFORMATION

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Precautionary Statements

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves